Evidence map›Paper›PMID 32157642›Full record

ReviewHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2020

Italian Society of Arterial Hypertension (SIIA) Position Paper on the Role of Renal Denervation in the Management of the Difficult-to-Treat Hypertensive Patient.

Rosa Maria Bruno, Stefano Taddei, Claudio Borghi, Furio Colivicchi, Giovambattista Desideri, Guido Grassi, Alberto Mazza, Maria Lorenza Muiesan, Gianfranco Parati, Roberto Pontremoli and 3 more

Abstract readConsensus StatementReview
PubMed Publisher
In one paragraph

Review in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Guideline
  2. Systematic Review Article: New Drug Strategies for Treating Resistant Hypertension-the Importance of a Mechanistic, Personalized Approach.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Pooled it
  3. Interventional Treatment of Arterial Hypertension in The Modern Era: An Updated Review from the Young Investigator Group of the European Society of Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Review
  4. Cost-Effectiveness and Budget Impact Analysis of Radiofrequency Renal Denervation for Uncontrolled and Resistant Hypertension in Italy.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  5. Review
  6. Article
  7. Renal Denervation as a Novel Therapeutic Approach for Resistant Hypertension: Mechanisms, Efficacy and Future Directions.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Review
  8. In these cases, I treat hypertension with renal ablation.European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
  9. Article
  10. Renal Denervation in End-Stage Renal Disease: Current Evidence and Perspectives.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Review
  11. The enigma of resistant hypertension: from lifestyle changes and pharmacological treatment to renal denervation.European heart journal supplements : journal of the European Society of Cardiology · 2022
    Article
  12. Article
  13. Advances in the Treatment Strategies in Hypertension: Present and Future.Journal of cardiovascular development and disease · 2022
    Review
  14. Review
  15. A Japan nationwide web-based survey of patient preference for renal denervation for hypertension treatment.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Article
  16. Article
  17. Review
  18. Renal Denervation in Daily Practice: If So, How?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 2 countries.

Rosa Maria BrunoDepartment of Clinical and Experimental Medicine, University of Pisa, c/o Ospedale Santa Chiara, Building #8, Via Roma 67, 56124, Pisa, Italy. rosa-maria.bruno@inserm.fr.ORCID http://orcid.org/0000-0002-6107-3356
Stefano TaddeiDepartment of Clinical and Experimental Medicine, University of Pisa, c/o Ospedale Santa Chiara, Building #8, Via Roma 67, 56124, Pisa, Italy.
Claudio BorghiUniversity of Bologna, Bologna, Italy.
Furio ColivicchiOspedale San Filippo Neri, Rome, Italy.
Giovambattista DesideriUniversity of L'Aquila, L'Aquila, Italy.
Guido GrassiUniversity of Milano-Bicocca, Milan, Italy.
Alberto MazzaAULSS 5 Polesana, Internal Medicine, Rovigo General Hospital, Rovigo, Italy.
Maria Lorenza MuiesanUniversity of Brescia, Brescia, Italy.
Gianfranco ParatiIstituto Auxologico Italiano, IRCCS, Ospedale S.Luca, Milan, Italy.
Roberto PontremoliUniversità degli Studi, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Bruno TrimarcoUniversity Federico II, Naples, Italy.
Massimo VolpeDivision of Cardiology, University of Rome Sapienza, Sant'Andrea Hospital, Rome, Italy.
Claudio FerriUniversity of L'Aquila, L'Aquila, Italy.
University of L'Aquila · ITUniversity of Pisa · ITFederico II University Hospital · ITIRCCS Istituto Auxologico Italiano · ITIstituto Neurologico Mediterraneo · ITOspedale Policlinico San Martino · ITOspedale San Filippo Neri · ITUniversity of Bologna · ITUniversity of Brescia · ITUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal denervation is a device-based procedure for hypertension for which safety and efficacy has been demonstrated. At present, its clinical use is still matter of debate, despite the most recent clinical trials have shown promising results with new-generation devices in various hypertensive populations. This position paper was deemed necessary by the Italian Society of Arterial Hypertension, in order to provide indications about the applications of renal denervation in the clinical setting. A state-of-the art review of the literature, focusing on safety and efficacy data, is provided. Furthermore, based on current evidence and expert consensus, clinical profiles of possible candidates for renal denervation are proposed. The selection process should take into account not only blood pressure values, global cardiovascular risk profile, but also drug adherence and tolerability and patient preferences. This position paper also defines minimum requirements for renal denervation selection centers and a flowchart for the difficult-to-treat hypertensive patient. Further studies are needed to support these preliminary indications, which are based on expert-consensus only.

Indexed as

Ablation TechniquesArterial PressureHypertensionKidneyRenal ArterySympathectomyAntihypertensive AgentsClinical Decision-MakingDecision Support TechniquesDrug ResistanceHumansMedication AdherencePatient SafetyPatient SelectionRisk FactorsTreatment OutcomeAntihypertensive AgentsAdherenceHypertensionPatient preferencesPatient selectionRenal denervation

Identifiers

PMID32157642
OpenAlexW3010891615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.