ArticleBrain structure & function2020
Principles of temporal association cortex organisation as revealed by connectivity gradients.
Article in Brain structure & function, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Cortical Gradients Support Mental Time Travel into the Past and Future: Evidence from Activation Likelihood Estimation Meta-analysis.Neuropsychology review · 2026Pooled it
- Anchoring the human olfactory system within a functional gradient.NeuroImage · 2020Pooled it
- Multivariate Association Between Functional Connectivity Gradients and Cognition in Schizophrenia Spectrum Disorders.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Multiscale gradients of corticopontine structural connectivity.Scientific reports · 2025Article
- Gradients of Brain Organization: Smooth Sailing from Methods Development to User Community.Neuroinformatics · 2024Review
- Hippocampal connectivity patterns echo macroscale cortical evolution in the primate brain.Nature communications · 2024Article
- Exploring Cortical and Hippocampal Changes in Temporal Lobe Epilepsy Using Automated MRI Segmentation Techniques.International journal of general medicine · 2024Article
- Evaluating functional brain organization in individuals and identifying contributions to network overlap.bioRxiv : the preprint server for biology · 2023Article
- Correspondence of functional connectivity gradients across human isocortex, cerebellum, and hippocampus.Communications biology · 2023Article
- Evaluating functional brain organization in individuals and identifying contributions to network overlap.Imaging neuroscience (Cambridge, Mass.) · 2023Article
- Conduct disorder symptomatology is associated with an altered functional connectome in a large national youth sample.Development and psychopathology · 2022Article
- Frontotemporal dementia: A unique window on the functional role of the temporal lobes.Handbook of clinical neurology · 2022Review
- Connectivity gradients on tractography data: Pipeline and example applications.Human brain mapping · 2021Article
- Structural Connectivity Gradients of the Temporal Lobe Serve as Multiscale Axes of Brain Organization and Cortical Evolution.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- A Common Space Approach to Comparative Neuroscience.Annual review of neuroscience · 2021Article
- Article
- Structural and Functional Brain Parameters Related to Cognitive Performance Across Development: Replication and Extension of the Parieto-Frontal Integration Theory in a Single Sample.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Perspectives given by structural connectivity bridge the gap between structure and function.Brain structure & function · 2020Article
- Article
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
To establish the link between structure and function of any large area of the neocortex, it is helpful to identify its principles of organisation. One way to establish such principles is to investigate how differences in whole-brain connectivity are structured across the area. Here, we use Laplacian eigenmaps on diffusion MRI tractography data to investigate the organisational principles of the human temporal association cortex. We identify three overlapping gradients of connectivity that are, for the most part, consistent across hemispheres. The first gradient reveals an inferior-superior organisation of predominantly longitudinal tracts and separates visual and auditory unimodal and multimodal cortices. The second gradient radiates outward from the posterior middle temporal cortex with the arcuate fascicle as a distinguishing feature; the third gradient is concentrated in the anterior temporal lobe and emanates towards its posterior end. We describe the functional relevance of each of these gradients through the meta-analysis of data from the neuroimaging literature. Together, these results unravel the overlapping dimensions of structural organization of the human temporal cortex and provide a framework underlying its functional multiplicity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.