ArticlePediatric nephrology (Berlin, Germany)2020
A longitudinal examination of parent-reported emotional-behavioral functioning of children with mild to moderate chronic kidney disease.
Article in Pediatric nephrology (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00327860 (Chronic Kidney Disease in Children Prospective Cohort Study), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)
Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Ratings of parenting stress in mild to moderate chronic kidney disease in children: a pilot investigation.Pediatric nephrology (Berlin, Germany) · 2026Article
- Emotional, behavioural and adaptive function in children with chronic kidney disease: the Kids with CKD (KCAD) study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Now what: navigating care of maternal/fetal dyads with bilateral renal agenesis after RAFT. A physician and parent point of view.Pediatric nephrology (Berlin, Germany) · 2025Article
- COVID-19 Associated Worry and Emotional Distress in Youth and Young Adults with Chronic Kidney Disease.Annals of pediatrics · 2025Article
- Mental health and social-emotional functioning in children and adolescents with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2024Review
- Socioeconomic Position and Health Among Children and Adolescents With CKD Across the Life-Course.Kidney international reports · 2024Review
- Transition of care: lessons from the Standardizing Care to Improve Outcomes in Pediatric End Stage Renal Disease (SCOPE) dialysis collaborative.Pediatric nephrology (Berlin, Germany) · 2024Article
- Arterial Health Markers in Relation to Behavior and Cognitive Outcomes at School Age.Journal of the American Heart Association · 2024Article
- Longitudinal changes of health-related quality of life in childhood chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2023Article
- The pressure's on: understanding neurocognitive and psychological associations with pediatric hypertension to inform comprehensive care.Pediatric nephrology (Berlin, Germany) · 2021Review
- Neurocognition in Pediatric Chronic Kidney Disease: A Review of Data From the Chronic Kidney Disease in Children (CKiD) Study.Seminars in nephrology · 2021Review
- A longitudinal analysis of the effect of anemia on health-related quality of life in children with mild-to-moderate chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2020Article
Corrections and comments
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Authors and funding
11 authors at 8 institutions in 1 country.
Funding
Abstract
backgroundChildren with mild to moderate chronic kidney disease (CKD) are at increased risk for deficits in neurocognition. Less is known about how CKD affects emotional-behavioral functioning in this population.
methodsParent ratings of emotional-behavioral functioning at baseline and over time were examined for 845 children with mild to moderate CKD using the Behavior Assessment System for Children, Second Edition Parent Rating Scales (BASC-2 PRS). Associations with demographic and disease-related predictors were also examined.
resultsChildren with mild to moderate CKD had parent-reported emotional-behavioral functioning largely within normal limits, at baseline and over time. The proportion with T-scores at least 1 SD above the mean was 24% for Internalizing Problems and 28% for Attention Problems. A greater proportion of participants scored lower than expected (worse) on scales measuring adaptive skills (25%). Persistent hypertension predicted attention problems (β = 1.59, 95% CI = 0.24 to 2.94, p < 0.02) and suggested worse behavioral symptoms (β = 1.36, 95% CI = - 0.01 to 2.73, p = 0.05). Participants with proteinuria at baseline, but not at follow-up, had fewer attention problems than participants whose proteinuria had not resolved (β = - 3.48, CI = - 6.79 to - 0.17, p < 0.04). Glomerular diagnosis was related to fewer (β = - 2.68, 95% CI = - 4.93 to - 0.42, p < 0.02) internalizing problems.
conclusionsAlthough children with CKD generally have average emotional-behavioral parent ratings, a notable percentage of the population may be at risk for problems with attention and adaptive behavior. Providers working with this population should facilitate psychosocial referrals when indicated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.