Evidence map›Paper›PMID 32157385›Full record

ArticleActa neuropathologica2020

Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features.

Emily A Sloan, Stephanie Hilz, Rohit Gupta, Cathryn Cadwell, Biswarathan Ramani, Jeffrey Hofmann, Cassie N Kline, Anu Banerjee, Alyssa Reddy, Nancy Ann Oberheim Bush and 28 more

Abstract read
In one paragraph

Article in Acta neuropathologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  12. Glioma.Nature reviews. Disease primers · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Emily A SloanDepartment of Pathology, University of California, San Francisco, CA, USA.
Stephanie HilzDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Rohit GuptaDepartment of Pathology, University of California, San Francisco, CA, USA.
Cathryn CadwellDepartment of Pathology, University of California, San Francisco, CA, USA.
Biswarathan RamaniDepartment of Pathology, University of California, San Francisco, CA, USA.
Jeffrey HofmannDepartment of Pathology, University of California, San Francisco, CA, USA.
Cassie N KlineDivision of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, USA.
Anu BanerjeeDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Alyssa ReddyDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Nancy Ann Oberheim BushDepartment of Neurology, University of California, San Francisco, CA, USA.
Susan ChangDivision of Neuro-Oncology, Department of Neurological Surgery, University of California, San Francisco, CA, USA.
Steve BraunsteinDepartment of Radiation Oncology, University of California, San Francisco, CA, USA.
Edward F ChangDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Corey RaffelDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Nalin GuptaDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Peter P SunDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
John Y H KimDepartment of Pediatric Neurosurgery, Kaiser Permanente Oakland Medical Center, Oakland, CA, USA.
Gregory MoesDepartment of Pathology, Kaiser Permanente Oakland Medical Center, Oakland, CA, USA.
Elizabeth AlvaDivision of Hematology and Oncology, Children's of Alabama, University of Alabama at Birmingham, Birmingham, AL, USA.
Rong LiDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Carol S BruggersDivision of Pediatric Hematology-Oncology, Department of Pediatrics, University of Utah, Salt Lake City, UT, USA.
Mouied AlashariDepartment of Pathology, University of Utah, Salt Lake City, UT, USA.
Cynthia WetmoreDepartment of Hematology/Oncology, Phoenix Children's Hospital, Phoenix, AZ, USA.
Shipra GargDepartment of Pathology, Phoenix Children's Hospital, Phoenix, AZ, USA.
Megan DishopDepartment of Pathology, Phoenix Children's Hospital, Phoenix, AZ, USA.
Jessica Van ZiffleDepartment of Pathology, University of California, San Francisco, CA, USA.
Courtney OnoderaDepartment of Pathology, University of California, San Francisco, CA, USA.
Patrick DevineDepartment of Pathology, University of California, San Francisco, CA, USA.
James P GrenertDepartment of Pathology, University of California, San Francisco, CA, USA.
Julieann C LeeDepartment of Pathology, University of California, San Francisco, CA, USA.
Joanna J PhillipsDepartment of Pathology, University of California, San Francisco, CA, USA.
Melike PekmezciDepartment of Pathology, University of California, San Francisco, CA, USA.
Tarik TihanDepartment of Pathology, University of California, San Francisco, CA, USA.
Andrew W BollenDepartment of Pathology, University of California, San Francisco, CA, USA.
Mitchel S BergerDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Joseph F CostelloDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Arie PerryDepartment of Pathology, University of California, San Francisco, CA, USA.ORCID 0000-0002-8300-7261
David A SolomonDepartment of Pathology, University of California, San Francisco, CA, USA. david.solomon@ucsf.edu.ORCID 0000-0003-4571-7999

Funding

Tissue CoreP50CA097257 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joseph F Costello · 2002 to 2026
$57.4M
Research Training in Childhood CancerT32CA128583 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Eric Alejandro Sweet-Cordero · 2007 to 2026
$6.0M
Cohesin gene mutations in tumorigenesisDP5OD021403 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SOLOMON, DAVID A. · 2015 to 2019
$2.0M
NCI NIH HHS P50 CA097257NCI NIH HHS T32 CA128583NIH HHS DP5 OD021403
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultChildChild, PreschoolFemaleGenetic Predisposition to DiseaseGerm-Line MutationGliomaHumansLi-Fraumeni SyndromeMaleTumor Suppressor Protein p53Young AdultTumor Suppressor Protein p53

Identifiers

PMID32157385
PMCPMC7183424

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.