Evidence map›Paper›PMID 32156775›Full record

ArticleCancer research2020

TAp63-Regulated miRNAs Suppress Cutaneous Squamous Cell Carcinoma through Inhibition of a Network of Cell-Cycle Genes.

Andrew John Davis, Maksym Tsinkevich, Jason Rodencal, Hussein A Abbas, Xiao-Hua Su, Young-Jin Gi, Bin Fang, Kimal Rajapakshe, Cristian Coarfa, Preethi H Gunaratne and 3 more

Open access · greenAbstract readComment
In one paragraph

Article in Cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. miR-497 Target Gene Regulatory Network in Angiosarcoma.Molecular cancer research : MCR · 2024
    Article
  5. Review
  6. Target gene regulatory network of miR-497 in angiosarcoma.bioRxiv : the preprint server for biology · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Molecular Mechanisms of Cutaneous Squamous Cell Carcinoma.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Article
  13. Review
  14. Oh, the Mutations You'll Acquire! A Systematic Overview of Cutaneous Squamous Cell Carcinoma.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2021
    Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Andrew John DavisDepartment of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Maksym TsinkevichDepartment of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.ORCID 0000-0002-6374-0650
Jason RodencalDepartment of Biology, Stanford University School of Medicine, Stanford, California.
Hussein A AbbasHematology/Oncology Fellowship Program, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Xiao-Hua SuDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Young-Jin GiDepartment of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Bin FangDepartment of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Kimal RajapaksheDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
Cristian CoarfaDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-4183-4939
Preethi H GunaratneDepartment of Biology and Biochemistry, University of Houston, Houston, Texas.
John M KoomenDepartment of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.ORCID 0000-0002-3818-1762
Kenneth Y TsaiDepartment of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Elsa R FloresDepartment of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida. Elsa.Flores@moffitt.org.ORCID 0000-0002-6173-2403
Moffitt Cancer Center · USThe University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · USStanford University · USUniversity of Houston · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9M
Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2019 to 2026
$14.7M
TRAINING FOR ACADEMIC ONCOLOGY/HEMATOLOGYT32CA009666 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Michael Davies, Courtney DiNardo · 1994 to 2026
$9.8M
Identification of non-coding RNAs to therapeutically target undruggable pathways in metastatic lung adenocarcinoma and squamous cell carcinomaR35CA197452 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI FLORES, ELSA R · 2016 to 2022
$6.4M
Center for Clinical and Translational Sciences (CCTS)TL1TR000369 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$1.9M
NCATS NIH HHS TL1 TR000369NCI NIH HHS P30 CA016672NCI NIH HHS P30 CA076292NCI NIH HHS P30 CA125123NCI NIH HHS R35 CA197452NCI NIH HHS T32 CA009666NIEHS NIH HHS P30 ES030285
6 · The paper itself

Abstract

TAp63 is a p53 family member and potent tumor and metastasis suppressor. Here, we show that

Indexed as

Carcinoma, Squamous CellMicroRNAsSkin NeoplasmsAnimalsAurora Kinase ACell ProliferationHumansKinesinsMembrane ProteinsMiceProtein Serine-Threonine KinasesProtein-Tyrosine KinasesProteomicsUltraviolet RaysAURKA protein, humanAurora Kinase AKIF18B protein, humanKinesinsMembrane ProteinsMicroRNAsMIRN497 microRNA, humanPKMYT1 protein, humanProtein Serine-Threonine KinasesProtein-Tyrosine Kinases

Identifiers

PMID32156775
PMCPMC7299759
OpenAlexW3011530118

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.