Evidence map›Paper›PMID 32156750›Full record

ArticleGenetics2020

Development of the Proximal-Anterior Skeletal Elements in the Mouse Hindlimb Is Regulated by a Transcriptional and Signaling Network Controlled by

Katherine Q Chen, Naoyuki Tahara, Aaron Anderson, Hiroko Kawakami, Sho Kawakami, Ryuichi Nishinakamura, Pier Paolo Pandolfi, Yasuhiko Kawakami

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Cereblon influences the timing of muscle differentiation inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Katherine Q ChenDepartment of Genetics, Cell Biology and Development.
Naoyuki TaharaDepartment of Genetics, Cell Biology and Development.
Aaron AndersonDepartment of Genetics, Cell Biology and Development.ORCID 0000-0003-1797-5229
Hiroko KawakamiDepartment of Genetics, Cell Biology and Development.
Sho KawakamiDepartment of Genetics, Cell Biology and Development.ORCID 0000-0002-5413-7171
Ryuichi NishinakamuraDepartment of Kidney Development, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan 860-0811.
Pier Paolo PandolfiCancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215.
Yasuhiko KawakamiDepartment of Genetics, Cell Biology and Development kawak005@umn.edu.ORCID 0000-0002-0043-9705
Institut thématique Génétique, génomique et bioinformatique · FRUniversity of Minnesota · USBeth Israel Deaconess Medical Center · USKumamoto University · JP

Funding

Genetic Regulation of Progenitor Cells in Appendicular Skeletal DevelopmentR01AR064195 · NIAMS · UNIVERSITY OF MINNESOTA · PI KAWAKAMI, YASUHIKO · 2013 to 2022
$3.3M
NIAMS NIH HHS R01 AR064195
6 · The paper itself

Abstract

The vertebrate limb serves as an experimental paradigm to study mechanisms that regulate development of the stereotypical skeletal elements. In this study, we simultaneously inactivated

Indexed as

Bone DevelopmentSignal TransductionAnimalsDNA-Binding ProteinsFemurGene Expression Regulation, DevelopmentalHomeodomain ProteinsMiceNerve Tissue ProteinsPromyelocytic Leukemia Zinc Finger ProteinRNA, MessengerTibiaTranscription FactorsZinc Finger Protein Gli3DNA-Binding ProteinsGli3 protein, mouseHomeodomain ProteinsHoxb6 protein, mouseNerve Tissue ProteinsPromyelocytic Leukemia Zinc Finger ProteinRNA, MessengerSall4 protein, mouseTranscription FactorsVsx2 protein, mouseZbtb16 protein, mouseZinc Finger Protein Gli3limbPlzfproximal-anterior skeletonSall4Sonic Hedgehog-Gli3

Identifiers

PMID32156750
PMCPMC7198279
OpenAlexW3012176713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.