ArticleJournal of structural biology2020
Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy.
Article in Journal of structural biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Volume electron microscopy reveals oligodendrocyte axon selection patterns and spatial assembly of myelin and nodes.iScience · 2026Article
- A model of free sialic acid storage disorder reveals hypomyelinating leukodystrophy and Purkinje cell degeneration.Disease models & mechanisms · 2026Article
- In situ quantification of ribosome number by electron tomography.Journal of microscopy · 2025Article
- Developmental axon diameter growth of central nervous system axons does not depend on ensheathment or myelination by oligodendrocytes.bioRxiv : the preprint server for biology · 2025Article
- Oligodendrocyte-axon metabolic coupling is mediated by extracellular KNature neuroscience · 2024Article
- Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus.iScience · 2024Article
- Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity.eLife · 2023Article
- Case report: A novelFrontiers in genetics · 2023Article
- Article
- Volume electron microscopy: analyzing the lung.Histochemistry and cell biology · 2021Review
- Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia.PLoS biology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in electron microscopy including improved imaging techniques and state-of-the-art detectors facilitate imaging of larger tissue volumes with electron microscopic resolution. In combination with genetic tools for the generation of mouse mutants this allows assessing the three-dimensional (3D) characteristics of pathological features in disease models. Here we revisited the axonal pathology in the central nervous system of a mouse model of spastic paraplegia type 2, the Plp
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Registered trials
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