Evidence map›Paper›PMID 32156000›Full record

ArticleInternational journal of molecular sciences2020

Chronic Exposure to Low Concentration Lead Chloride-Induced Anxiety and Loss of Aggression and Memory in Zebrafish.

Ngoc Hieu Bui Thi, Ngoc Anh Nguyen Thi, Gilbert Audira, Petrus Siregar, Sung-Tzu Liang, Jong-Chin Huang, Chung-Der Hsiao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 60 citations in OpenAlex.

  1. Molecular and cellular mechanisms of lead-induced neurotoxicity: comparative insights from rodent and zebrafish models.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  2. Article
  3. Anthropogenic Underwater Noise Induces Anxiety-like Behavior in Zebrafish.Animals : an open access journal from MDPI · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ngoc Hieu Bui ThiDepartment of Chemistry, Chung Yuan Christian University, Taoyuan 32023, Taiwan.
Ngoc Anh Nguyen ThiDepartment of Bioscience Technology, Chung Yuan Christian University, Taoyuan 32023, Taiwan.
Gilbert AudiraDepartment of Chemistry, Chung Yuan Christian University, Taoyuan 32023, Taiwan.
Petrus SiregarDepartment of Bioscience Technology, Chung Yuan Christian University, Taoyuan 32023, Taiwan.
Sung-Tzu LiangDepartment of Bioscience Technology, Chung Yuan Christian University, Taoyuan 32023, Taiwan.ORCID 0000-0002-4068-4430
Jong-Chin HuangDepartment of Applied Chemistry, National Pingtung University, Pingtung 90003, Taiwan.ORCID 0000-0003-3997-1683
Chung-Der HsiaoDepartment of Chemistry, Chung Yuan Christian University, Taoyuan 32023, Taiwan.ORCID 0000-0002-6398-8672
Chung Yuan Christian University · TWNational Pingtung University · TW

Funding

Ministry of Science Technology of Taiwan MOST 107-2622-B-033-001-CC2 and MOST 108-2622-B-033-001-CC2 to CDH; MOST 106-2633-B-153-001- and MOST 107-2633-B-153-001- to JCH
6 · The paper itself

Abstract

Lead and lead-derived compounds have been extensively utilized in industry, and their chronic toxicity towards aquatic animals has not been thoroughly addressed at a behavioral level. In this study, we assessed the risk of exposure to lead at a waterborne environmental concentration in adult zebrafish by behavioral and biochemical analyses. Nine tests, including three-dimension (3D) locomotion, novel tank exploration, mirror biting, predator avoidance, social interaction, shoaling, circadian rhythm locomotor activity, color preference, and a short-term memory test, were performed to assess the behavior of adult zebrafish after the exposure to 50 ppb PbCl

Indexed as

AggressionAnimalsAnxietyBehavior, AnimalEcotoxicologyEnvironmental ExposureHydrocortisoneLeadMelatoninMemory, Short-TermSerotoninZebrafishHydrocortisoneLeadlead chlorideMelatoninSerotoninbehaviorecotoxicityleadneurotransmitterzebrafish

Identifiers

PMID32156000
PMCPMC7084271
OpenAlexW3009956067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.