Evidence map›Paper›PMID 32155992›Full record

ArticleInternational journal of molecular sciences2020

Sulfonamide Inhibition Studies of an α-Carbonic Anhydrase from

Andrea Angeli, Mariana Pinteala, Stelian S Maier, Bogdan C Simionescu, Akram A Da'dara, Patrick J Skelly, Claudiu T Supuran

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Development of Praziquantel sulphonamide derivatives as antischistosomal drugs.Journal of enzyme inhibition and medicinal chemistry · 2022
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Andrea AngeliDipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Via U. Schiff 6, 50019 Sesto Fiorentino, Florence, Italy.ORCID 0000-0002-1470-7192
Mariana PintealaCentre of Advanced Research in Bionanoconjugates and Biopolymers Department, "Petru Poni" Institute of Macromolecular Chemistry, 700487 Iasi, Romania.ORCID 0000-0002-2324-0088
Stelian S MaierCentre of Advanced Research in Bionanoconjugates and Biopolymers Department, "Petru Poni" Institute of Macromolecular Chemistry, 700487 Iasi, Romania.ORCID 0000-0001-9929-2821
Bogdan C SimionescuCentre of Advanced Research in Bionanoconjugates and Biopolymers Department, "Petru Poni" Institute of Macromolecular Chemistry, 700487 Iasi, Romania.
Akram A Da'daraDepartment of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.
Patrick J SkellyDepartment of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.
Claudiu T SupuranDipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Via U. Schiff 6, 50019 Sesto Fiorentino, Florence, Italy.ORCID 0000-0003-4262-0323
Tufts University · USUniversity of Florence · ITGheorghe Asachi Technical University of Iași · RO

Funding

Inhibiting tegumental carbonic anhydrase as a novel treatment for schistosomiasisR21AI111011 · NIAID · TUFTS UNIVERSITY BOSTON · PI SKELLY, PATRICK J · 2014 to 2015
$436k
NIAID NIH HHS R21 AI111011
6 · The paper itself

Abstract

Schistosomiasis is a debilitating infection provoked by parasitic flatworms called schistosomes. The species

Indexed as

AnimalsAnthelminticsCarbonic Anhydrase InhibitorsCarbonic AnhydrasesHumansParasitic Sensitivity TestsSchistosoma mansoniSchistosomiasisStructure-Activity RelationshipSulfonamidesAnthelminticsCarbonic Anhydrase InhibitorsCarbonic AnhydrasesSulfonamidesblood flukecarbonic anhydraseinhibitorSchistosoma mansonischistosomiasissulfonamidetrematode

Identifiers

PMID32155992
PMCPMC7084386
OpenAlexW3009843847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.