Evidence map›Paper›PMID 32155982›Full record

ArticleInternational journal of environmental research and public health2020

Neutrophil-To-Lymphocyte and Platelet-To-Lymphocyte Ratios as Prognostic Markers of Survival in Patients with Head and Neck Tumours-Results of a Retrospective Multicentric Study.

Zsuzsanna Szilasi, Valéria Jósa, Zsombor Zrubka, Tünde Mezei, Tamás Vass, Keresztély Merkel, Frigyes Helfferich, Zsolt Baranyai

Abstract readMulticenter Study
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pre-treatment neutrophil-to-lymphocyte ratio is an independent prognostic factor in head and neck squamous cell carcinoma: Meta-analysis and trial sequential analysis.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2022
    Pooled it
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  8. Prognostic Significance of Pre-Treatment Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Head and Neck Malignancies.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
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  11. Correlation of the Neutrophil-to-Lymphocyte Ratio with the Middle Ear Risk Index in Patients with Chronic Otitis Media.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
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  17. The prognostic value of red cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) in radiotherapy for oropharyngeal cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zsuzsanna SzilasiDepartment of Otorhinolaryngology and Head and Neck Surgery, HDF Medical Centre, H-1134 Budapest, Hungary.
Valéria JósaDepartment of Otorhinolaryngology and Head and Neck Surgery, Jahn Ferenc Hospital, H-1204 Budapest, Hungary.ORCID 0000-0002-2600-1867
Zsombor ZrubkaDepartment of Health Economics, Corvinus University of Budapest, H-1093 Budapest, Hungary.ORCID 0000-0002-1992-6087
Tünde MezeiDepartment of Urology, Jahn Ferenc Hospital, H-1204 Budapest, Hungary.
Tamás VassDepartment of Surgery, Szent Imre Hospital, H-1115 Budapest, Hungary.
Keresztély MerkelDepartment of Surgery, Szent Imre Hospital, H-1115 Budapest, Hungary.
Frigyes HelfferichDepartment of Otorhinolaryngology and Head and Neck Surgery, HDF Medical Centre, H-1134 Budapest, Hungary.
Zsolt Baranyai1st Department of Surgery, Semmelweis University, H-1082 Budapest, Hungary.ORCID 0000-0003-2487-0302

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) may be useful for drawing conclusions about the survival of head and neck squamous cell carcinoma (HNSCC) patients.

methodsClinical data of 156 patients managed for HNSCC at two head and neck surgery centres were analyzed retrospectively. We studied the relationships between survival and PLR as well as NLR.

resultsWith regards to 5-year survival, the difference between the two groups with PLR values lower or higher than the threshold was statistically significant (

conclusionIn HNSCC patients, a high NLR may be considered as an independent risk factor for 5-year overall survival.

Indexed as

LymphocytesNeutrophilsBiomarkers, TumorBlood PlateletsFemaleHead and Neck NeoplasmsHumansLymphocyte CountMaleRetrospective StudiesBiomarkers, Tumorhead and neck neoplasmsneutrophil-to-lymphocyte ratioplatelet-to-lymphocyte ratiosurvival

Identifiers

PMID32155982
PMCPMC7084240

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.