Evidence map›Paper›PMID 32155891›Full record

ArticleMolecules (Basel, Switzerland)2020

A Second Look at the Crystal Structures of

Florian Nachon, Terrone L Rosenberry, Israel Silman, Joel L Sussman

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Chemical Profile and Bioinsecticidal Nanoemulsion ofPlants (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Review
  5. Acetylcholinesterase: Structure, dynamics, and interactions with organophosphorus compounds.Protein science : a publication of the Protein Society · 2025
    Review
  6. Article
  7. Article
  8. Insecticidal and Bactericidal Activities ofTurkish journal of pharmaceutical sciences · 2025
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Florian NachonDépartement de Toxicologie et Risques Chimiques, Institut de Recherche Biomédicale des Armées, 91220 Brétigny-sur-Orge, France.ORCID 0000-0003-0293-2429
Terrone L RosenberryDepartments of Neuroscience and Pharmacology, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA.ORCID 0000-0003-3579-7681
Israel SilmanDepartment of Neurobiology, Weizmann Institute of Science, 7610001 Rehovot, Israel.
Joel L SussmanDepartment of Structural Biology, Weizmann Institute of Science, 7610001 Rehovot, Israel.ORCID 0000-0003-0306-3878
Weizmann Institute of Science · ILJacksonville College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over recent decades, crystallographic software for data processing and structure refinement has improved dramatically, resulting in more accurate and detailed crystal structures. It is, therefore, sometimes valuable to have a second look at "old" diffraction data, especially when earlier interpretation of the electron density maps was rather difficult. Here, we present updated crystal structures of

Indexed as

Drug DesignAcetylcholinesteraseAnimalsBinding SitesCatalysisCatalytic DomainCholinesterase InhibitorsDrosophila melanogasterInsecticidesModels, MolecularMolecular StructureProtein BindingProtein ConformationStructure-Activity RelationshipTacrineAcetylcholinesteraseCholinesterase InhibitorsInsecticidesTacrineacetylcholinesteraseDrosophilainhibitorsX-ray structures

Identifiers

PMID32155891
PMCPMC7179448
OpenAlexW3009696178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.