Evidence map›Paper›PMID 32155882›Full record

ArticleMolecules (Basel, Switzerland)2020

Deciphering Pathways for Carotenogenesis in Haloarchaea.

Micaela Giani, Jose María Miralles-Robledillo, Gloria Peiró, Carmen Pire, Rosa María Martínez-Espinosa

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. A New Era for Using Natural Pigments: The Case of the CBiotechnology and applied biochemistry · 2026
    Review
  4. Recent Advances in Understanding Bio-Compounds from Haloarchaea.Journal of microbiology and biotechnology · 2026
    Review
  5. Article
  6. Microbial conversion of biodiesel waste for carotenoid production.Frontiers in bioengineering and biotechnology · 2026
    Article
  7. Article
  8. Article
  9. Microbial Bacterioruberin: A Comprehensive Review.Indian journal of microbiology · 2024
    Review
  10. Halocins and CMarine drugs · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Micaela GianiBiochemistry and Molecular Biology Division, Agrochemistry and Biochemistry Department, Faculty of Sciences, University of Alicante, Ap. 99, 03690 Alicante, Spain.ORCID 0000-0002-7558-7278
Jose María Miralles-RobledilloBiochemistry and Molecular Biology Division, Agrochemistry and Biochemistry Department, Faculty of Sciences, University of Alicante, Ap. 99, 03690 Alicante, Spain.ORCID 0000-0003-0471-373X
Gloria PeiróPathology Department and Research Unit; University General Hospital of Alicante; Pintor Baeza 12, 03010 Alicante, Spain.
Carmen PireBiochemistry and Molecular Biology Division, Agrochemistry and Biochemistry Department, Faculty of Sciences, University of Alicante, Ap. 99, 03690 Alicante, Spain.
Rosa María Martínez-EspinosaBiochemistry and Molecular Biology Division, Agrochemistry and Biochemistry Department, Faculty of Sciences, University of Alicante, Ap. 99, 03690 Alicante, Spain.ORCID 0000-0003-2679-135X
University of Alicante · ESHospital General Universitario de Alicante Doctor Balmis · ES

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España RTI2018-099860-B-I00Universidad de Alicante VIGROB-309
6 · The paper itself

Abstract

Bacterioruberin and its derivatives have been described as the major carotenoids produced by haloarchaea (halophilic microbes belonging to the Archaea domain). Recently, different works have revealed that some haloarchaea synthetize other carotenoids at very low concentrations, like lycopene, lycopersene, cis- and trans-phytoene, cis- and trans-phytofluene, neo-β-carotene, and neo-α-carotene. However, there is still controversy about the nature of the pathways for carotenogenesis in haloarchaea. During the last decade, the number of haloarchaeal genomes fully sequenced and assembled has increased significantly. Although some of these genomes are not fully annotated, and many others are drafts, this information provides a new approach to exploring the capability of haloarchaea to produce carotenoids. This work conducts a deeply bioinformatic analysis to establish a hypothetical metabolic map connecting all the potential pathways involved in carotenogenesis in haloarchaea. Special interest has been focused on the synthesis of bacterioruberin in members of the

Indexed as

Metabolic Networks and PathwaysAntioxidantsCarotenoidsEuryarchaeotaGene Expression Regulation, BacterialGene Expression Regulation, EnzymologicGenome, BacterialGenomicsPhylogenyPigments, BiologicalAntioxidantsbacterioruberinCarotenoidsPigments, Biologicalantioxidantbacterioruberincarotenogenesiscarotenoidshaloarchaeanatural pigments

Identifiers

PMID32155882
PMCPMC7179442
OpenAlexW3009879947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.