Evidence map›Paper›PMID 32155876›Full record

ArticleNutrients2020

A Suboptimal Diet is Associated with Poorer Cognition: The NUDAD Project.

Jay L P Fieldhouse, Astrid S Doorduijn, Francisca A de Leeuw, Barbara J H Verhaar, Ted Koene, Linda M P Wesselman, Marian de van der Schueren, Marjolein Visser, Ondine van de Rest, Philip Scheltens and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Effect of a Vegan Diet on Alzheimer's Disease.International journal of molecular sciences · 2022
    Review
  9. Article
  10. In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function.International journal of molecular sciences · 2021
    Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jay L P FieldhouseAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081HZ Amsterdam, The Netherlands.
Astrid S DoorduijnAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081HZ Amsterdam, The Netherlands.
Francisca A de LeeuwAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081HZ Amsterdam, The Netherlands.
Barbara J H VerhaarAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081HZ Amsterdam, The Netherlands.
Ted KoeneAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081HZ Amsterdam, The Netherlands.
Linda M P WesselmanAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081HZ Amsterdam, The Netherlands.
Marian de van der SchuerenDepartment of Nutrition and Dietetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Public Health Research Institute Amsterdam, 1081HV Amsterdam, The Netherlands.
Marjolein VisserDepartment of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam and the Amsterdam Public Health Research Institute, 1081HV Amsterdam, The Netherlands.
Ondine van de RestDivision of Human Nutrition and Health, Wageningen University & Research, 6708WE Wageningen, The Netherlands.
Philip ScheltensAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081HZ Amsterdam, The Netherlands.
Maartje I KesterAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081HZ Amsterdam, The Netherlands.
Wiesje M van der FlierAlzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081HZ Amsterdam, The Netherlands.
Amsterdam Neuroscience · NLHAN University of Applied Sciences · NLVrije Universiteit Amsterdam · NLWageningen University & Research · NL

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek 057-14-004
6 · The paper itself

Abstract

Nutrition is one of the modifiable risk factors for cognitive decline and Alzheimer's disease (AD) dementia, and is therefore highly relevant in the context of prevention. However, knowledge of dietary quality in clinical populations on the spectrum of AD dementia is lacking, therefore we studied the association between dietary quality and cognitive impairment in Alzheimer's disease (AD) dementia, mild cognitive impairment (MCI) and controls. We included 357 participants from the NUDAD project (134 AD dementia, 90 MCI, 133 controls). We assessed adherence to dietary guidelines (components: vegetables, fruit, fibers, fish, saturated fat, trans-fat, salt, and alcohol), and cognitive performance (domains: memory, language, visuospatial functioning, attention, and executive functioning). In the total population, linear regression analyses showed a lower vegetable intake is associated with poorer global cognition, visuospatial functioning, attention and executive functioning. In AD dementia, lower total adherence to dietary guidelines and higher alcohol intake were associated with poorer memory, a lower vegetable intake with poorer global cognition and executive functioning, and a higher trans-fat intake with poorer executive functioning. In conclusion, a suboptimal diet is associated with more severely impaired cognition-this association is mostly attributable to a lower vegetable intake and is most pronounced in AD dementia.

Indexed as

Diet, HealthyEatingElder Nutritional Physiological PhenomenaFeeding BehaviorRecommended Dietary AllowancesVegetablesAlcohol DrinkingAlzheimer DiseaseCognitionCognitive DysfunctionDietary FatsExecutive FunctionFemaleHumansMaleMalnutritionDietary FatsTrans Fatty Acidsdementiafood intakemild cognitive impairmentneuropsychological functioningnutrition

Identifiers

PMID32155876
PMCPMC7146357
OpenAlexW3009311242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.