Evidence map›Paper›PMID 32155862›Full record

ArticleMicromachines2020

High-Throughput White Blood Cell (Leukocyte) Enrichment from Whole Blood Using Hydrodynamic and Inertial Forces.

Batzorig Lombodorj, Horas Cendana Tseng, Hwan-You Chang, Yen-Wen Lu, Namnan Tumurpurev, Chun-Wei Lee, Batdemberel Ganbat, Ren-Guei Wu, Fan-Gang Tseng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. LFC-Lab on a chip · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Batzorig LombodorjSchool of Information and Communication Technology, Mongolian University of Science and Technology, Ulaanbaatar 14191, Mongolia.
Horas Cendana TsengDepartment of Engineering and System Science, Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu 30013, Taiwan.
Hwan-You ChangDepartment of Life Science, National Tsing Hua University, Hsinchu 30013, Taiwan.
Yen-Wen LuDepartment of Biomechatronics Engineering, National Taiwan University, Taipei 10617, Taiwan.
Namnan TumurpurevDepartment of Mechanical Engineering, Mongolian University of Science and Technology, Ulaanbaatar 14191, Mongolia.
Chun-Wei LeeDepartment of Engineering and System Science, Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu 30013, Taiwan.
Batdemberel GanbatDepartment of Physics, Mongolian University of Science and Technology, Ulaanbaatar 14191, Mongolia.
Ren-Guei WuDepartment of Engineering and System Science, Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu 30013, Taiwan.
Fan-Gang TsengDepartment of Engineering and System Science, Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu 30013, Taiwan.
National Tsing Hua University · TWMongolian University of Science and Technology · MNNational Taiwan University · TW

Funding

Ministry of Science and Technology 106-2923-E-007 -004 -MY3
6 · The paper itself

Abstract

A microfluidic chip, which can separate and enrich leukocytes from whole blood, is proposed. The chip has 10 switchback curve channels, which are connected by straight channels. The straight channels are designed to permit the inertial migration effect and to concentrate the blood cells, while the curve channels allow the Dean flow to further classify the blood cells based on the cell sizes. Hydrodynamic suction is also utilized to remove smaller blood cells (e.g., red blood cell (RBC)) in the curve channels for higher separation purity. By employing the inertial migration, Dean flow force, and hydrodynamic suction in a continuous flow system, our chip successfully separates large white blood cells (WBCs) from the whole blood with the processing rates as high as 1 × 10

Indexed as

blood separationmicrofluidics

Identifiers

PMID32155862
PMCPMC7143169
OpenAlexW3009040772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.