Evidence map›Paper›PMID 32155745›Full record

ArticleBiomolecules2020

Hydroxylamine Analogue of Agmatine: Magic Bullet for Arginine Decarboxylase.

Mervi T Hyvönen, Tuomo A Keinänen, Gulgina K Nuraeva, Dmitry V Yanvarev, Maxim Khomutov, Elena N Khurs, Sergey N Kochetkov, Jouko Vepsäläinen, Alexander A Zhgun, Alex R Khomutov

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  5. Comparative Genomic Analysis Reveals Key Changes in the Genome ofInternational journal of molecular sciences · 2024
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  7. New Biocides Based onInternational journal of molecular sciences · 2024
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  8. Review
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  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Mervi T HyvönenSchool of Pharmacy, Biocenter Kuopio, University of Eastern Finland, Kuopio Campus, P.O. Box 1627, FI-70211 Kuopio, Finland.
Tuomo A KeinänenSchool of Pharmacy, Biocenter Kuopio, University of Eastern Finland, Kuopio Campus, P.O. Box 1627, FI-70211 Kuopio, Finland.
Gulgina K NuraevaResearch Center of Biotechnology, Russian Academy of Sciences, 119071 Moscow, Russia.
Dmitry V YanvarevEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, 119991 Moscow, Russia.
Maxim KhomutovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, 119991 Moscow, Russia.
Elena N KhursEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, 119991 Moscow, Russia.
Sergey N KochetkovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, 119991 Moscow, Russia.
Jouko VepsäläinenSchool of Pharmacy, Biocenter Kuopio, University of Eastern Finland, Kuopio Campus, P.O. Box 1627, FI-70211 Kuopio, Finland.
Alexander A ZhgunResearch Center of Biotechnology, Russian Academy of Sciences, 119071 Moscow, Russia.
Alex R KhomutovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, 119991 Moscow, Russia.
Engelhardt Institute of Molecular Biology · RUUniversity of Eastern Finland · FIRussian Academy of Sciences · RU

Funding

Academy of Finland 315487Russian Foundation for Basic Research 19-04-01173Russian Science Foundation 17-74-20049
6 · The paper itself

Abstract

The biogenic polyamines, spermine, spermidine (Spd) and putrescine (Put) are present at micro-millimolar concentrations in eukaryotic and prokaryotic cells (many prokaryotes have no spermine), participating in the regulation of cellular proliferation and differentiation. In mammalian cells Put is formed exclusively from

Indexed as

AgmatineCarboxy-LyasesEscherichia coli ProteinsAcremoniumAnimalsEscherichia coliMaleMiceAgmatinearginine decarboxylaseCarboxy-LyasesEscherichia coli ProteinsAcremonium chrysogenumarginine decarboxylaseEscherichia colinanomolar inhibitorornithine decarboxylaseO-substituted hydroxylaminePolyamines

Identifiers

PMID32155745
PMCPMC7175277
OpenAlexW3009448740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.