ArticleBiomaterials2020
Construction of vascular graft with circumferentially oriented microchannels for improving artery regeneration.
Article in Biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 88 citations in OpenAlex.
- Quantitative dynamic full-field optical coherence tomography for high-resolution intraoperative imaging of head and neck squamous cell carcinoma.Biomedical optics express · 2026Article
- Honeycomb-inspired porous biomimetic scaffold with specific adaptability to host cells behavior for bone repair.Journal of nanobiotechnology · 2026Article
- A bio-inspired screwed small-diameter vascular graft for endotheliazation and arterial regeneration.Bioactive materials · 2025Article
- A Tissue Engineering's Guide to Biomimicry.Macromolecular bioscience · 2025Review
- Advances in Drug Targeting, Drug Delivery, and Nanotechnology Applications: Therapeutic Significance in Cancer Treatment.Pharmaceutics · 2025Review
- Distinct cellular microenvironment with cytotypic effects regulates orderly regeneration of vascular tissues.Materials today. Bio · 2024Article
- Electrospun silk fibroin/fibrin vascular scaffold with superior mechanical properties and biocompatibility for applications in tissue engineering.Scientific reports · 2024Article
- Development of 3D printed electrospun vascular graft loaded with tetramethylpyrazine for reducing thrombosis and restraining aneurysmal dilatation.Burns & trauma · 2024Article
- Artificial intelligence applied in cardiovascular disease: a bibliometric and visual analysis.Frontiers in cardiovascular medicine · 2024Article
- Engineered muscle from micro-channeled PEG scaffold with magnetic FeMaterials today. Bio · 2023Article
- Bioprinted vascular tissue: Assessing functions from cellular, tissue to organ levels.Materials today. Bio · 2023Review
- Structural Features of Connective Tissue Formed around Resin Implants Subcutaneously Embedded in Dairy Cows.Animals : an open access journal from MDPI · 2023Article
- Recent Advances in Decellularized Matrix-Derived Materials for Bioink and 3D Bioprinting.Gels (Basel, Switzerland) · 2023Review
- VEGF combined with DAPT promotes tissue regeneration and remodeling in vascular grafts.Regenerative biomaterials · 2023Article
- Graded-Three-Dimensional Cell-Encapsulating Hydrogel as a Potential Biologic Scaffold for Disc Tissue Engineering.Tissue engineering and regenerative medicine · 2022Article
- Review
- CCL2 loaded microparticles promote acute patency in silk-based vascular grafts implanted in rat aortae.Acta biomaterialia · 2021Article
- Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing.Nature communications · 2021Article
- A simple method to align cells on 3D hydrogels using 3D printed molds.Biomedical engineering advances · 2021Article
- Micro- and nanoscale biophysical cues for cardiovascular disease therapy.Nanomedicine : nanotechnology, biology, and medicine · 2021Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
Design and fabrication of scaffolds with three-dimensional (3D) topological cues inducing regeneration of the neo-tissue comparable to native one remains a major challenge in both scientific and clinical fields. Here, we developed a well-designed vascular graft with 3D highly interconnected and circumferentially oriented microchannels by using the sacrificial sugar microfiber leaching method. The microchannels structure was capable of promoting the migration, oriented arrangement, elongation, and the contractile phenotype expression of vascular smooth muscle cells (VSMCs) in vitro. After implantation into the rat aorta defect model, the microchannels in vascular grafts simultaneously improved the infiltration and aligned arrangement of VSMCs and the oriented deposition of extracellular matrix (ECM), as well as the recruitment and polarization of macrophages. These positive results also provided protection and support for ECs growth, and ultimately accelerated the endothelialization. Our research provides a new strategy for the fabrication of grafts with the capability of inducing arterial regeneration, which could be further extended to apply in preparing other kinds of oriented scaffolds aiming to guide oriented tissue in situ regeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.