ArticleCurrent biology : CB2020
Sleep and Anesthesia: The Shared Circuit Hypothesis Has Been Put to Bed.
Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Periodic limb movements during sedation and general anesthesia in elderly patients: a prospective observational study.Journal of clinical monitoring and computing · 2026Observational
- Article
- A thalamic perspective of (un)consciousness in pharmacological and pathological states in humans.Brain communications · 2026Article
- Similarities and differences between natural sleep and urethane anesthesia.Scientific reports · 2025Article
- Neural Network Mechanisms Underlying General Anesthesia: Cortical and Subcortical Nuclei.Neuroscience bulletin · 2024Review
- Dopaminergic modulation of propofol-induced activation in VLPO neurons: the role of D1 receptors in sleep-promoting neural circuits.Frontiers in neuroscience · 2024Article
- Divergent Neural Activity in the VLPO During Anesthesia and Sleep.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- General anesthesia and sleep: like and unlike.Anesthesia and pain medicine · 2022Review
- Roles of Neuropeptide S in Anesthesia, Analgesia, and Sleep.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation.PLoS biology · 2021Article
- Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute activation of genetically defined sleep-promoting neurons in the preoptic hypothalamus does not facilitate anesthesia. This finding supports the notion that a mechanistic overlap between sleep and anesthesia does not explain the anesthetized brain.
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32155424What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.