Evidence map›Paper›PMID 32155166›Full record

ArticlePloS one2020

Effects of maternal hepatitis B surface antigen positive status on the pregnancy outcomes: A retrospective study in Xiamen, China, 2011-2018.

Yan Zhao, Yin-Ling Chen, Hai-Qu Song, Pei-Ying Huang, Li-Ying Wang, Wei Liu, Bing-Kun Huang, Fu-Ping Lv, Caoxin Huang, Bing Yan and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. [Correlation between hepatitis B virus infection and adverse pregnancy outcomes-a systematic review and meta-analysis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yan ZhaoDepartment of Endocrinology and Diabetes, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Yin-Ling ChenXiamen Diabetes Institute, Xiamen, China.ORCID 0000-0001-7966-2100
Hai-Qu SongXiamen University Medical College, Xiamen, China.
Pei-Ying HuangXiamen University Medical College, Xiamen, China.
Li-Ying WangXiamen University Medical College, Xiamen, China.
Wei LiuXiamen University Medical College, Xiamen, China.
Bing-Kun HuangXiamen University Medical College, Xiamen, China.
Fu-Ping LvXiamen University Medical College, Xiamen, China.
Caoxin HuangDepartment of Endocrinology and Diabetes, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Bing YanXiamen University Medical College, Xiamen, China.
Xue-Jun LiDepartment of Endocrinology and Diabetes, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Xiamen University · CNFirst Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHepatitis B virus infection is a major social and economic burden in developing countries, especially in China. We aimed to evaluate the effects of hepatitis B surface antigen (HBsAg) positive status on the pregnancy outcomes in the Chinese population.

methodsThis retrospective cohort study was performed using data from the Medical Birth Registry of Xiamen, China, from January 2011 to March 2018. Multivariate logistic regression analysis was used to assess the association between the HBsAg status and pregnancy outcomes.

resultsThis study included 3,789 HBsAg-positive women and 29, 648 non-exposed women. The HBsAg-positive pregnant women were slightly older in age (29.3±4.3 vs. 28.9±4.4, P< 0.001). Additionally, pregnant women with a positive HBsAg status had higher odds of gestational diabetes mellitus (GDM) (adjusted odds ratio [aOR], 1.13; 95% confidence interval [CI], 1.03-1.23), and cesarean delivery (aOR, 1.12; 95%CI, 1.03-1.21). The risk of infants being large or small-for-gestational age, having low-birth weight, and of macrosomia, preterm birth, and stillbirth did not differ significantly between the HBsAg-positive and-negative women.

conclusionIn Xiamen, China, the slightly higher risk of GDM and cesarean section in women positive for HBsAg should not be neglected. Further studies should be conducted to evaluate the effects of HBsAg positivity on the pregnancy outcomes in different ethnic populations.

Indexed as

Pregnancy OutcomeAdultChinaFemaleHepatitis B Surface AntigensHumansPregnancyRetrospective StudiesHepatitis B Surface Antigens

Identifiers

PMID32155166
PMCPMC7064202
OpenAlexW3011523857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.