Evidence map›Paper›PMID 32155143›Full record

ArticlePLoS neglected tropical diseases2020

Wolbachia strain wAu efficiently blocks arbovirus transmission in Aedes albopictus.

Maria Vittoria Mancini, Christie S Herd, Thomas H Ant, Shivan M Murdochy, Steven P Sinkins

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Infections ofViruses · 2025
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  5. ExploitingPathogens (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
  8. bioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. Pathogens and global health · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. RNA virome diversity andThe Journal of general virology · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maria Vittoria ManciniMRC- University of Glasgow- Centre for Virus Research, Glasgow, United Kingdom.
Christie S HerdMRC- University of Glasgow- Centre for Virus Research, Glasgow, United Kingdom.
Thomas H AntMRC- University of Glasgow- Centre for Virus Research, Glasgow, United Kingdom.
Shivan M MurdochyMRC- University of Glasgow- Centre for Virus Research, Glasgow, United Kingdom.
Steven P SinkinsMRC- University of Glasgow- Centre for Virus Research, Glasgow, United Kingdom.ORCID 0000-0002-2678-1832
MRC University of Glasgow Centre for Virus Research · GB

Funding

Medical Research Council MC_UU_12014/8Wellcome Trust 108508/A/15/ZWellcome Trust 108508/Z/15/ZWellcome Trust 202888/Z/16/Z
6 · The paper itself

Abstract

The global incidence of arboviral diseases transmitted by Aedes mosquitoes, including dengue, chikungunya, yellow fever, and Zika, has increased dramatically in recent decades. The release of Aedes aegypti carrying the maternally inherited symbiont Wolbachia as an intervention to control arboviruses is being trialled in several countries. However, these efforts are compromised in many endemic regions due to the co-localization of the secondary vector Aedes albopictus, the Asian tiger mosquito. Ae. albopictus has an expanding global distribution following incursions into a number of new territories. To date, only the wMel and wPip strains of Wolbachia have been reported to be transferred into and characterized in this vector. A Wolbachia strain naturally infecting Drosophila simulans, wAu, was selected for transfer into a Malaysian Ae. albopictus line to create a novel triple-strain infection. The newly generated line showed self-compatibility, moderate fitness cost and complete resistance to Zika and dengue infections.

Indexed as

AntibiosisAedesAnimalsArbovirusesArbovirus InfectionsDisease Transmission, InfectiousDrosophilaFemaleMaleMosquito VectorsWolbachia

Identifiers

PMID32155143
PMCPMC7083328
OpenAlexW3011522260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.