Evidence map›Paper›PMID 32155044›Full record

ArticleACS chemical biology2020

Harnessing β-Lactam Antibiotics for Illumination of the Activity of Penicillin-Binding Proteins in

Shabnam Sharifzadeh, Felix Dempwolff, Daniel B Kearns, Erin E Carlson

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Activity Profiling of Mycobacterial L,D-Transpeptidases.bioRxiv : the preprint server for biology · 2026
    Article
  7. Review
  8. ThebioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. ACS infectious diseases · 2024
    Article
  13. Penicillin-binding protein redundancy inApplied and environmental microbiology · 2024
    Article
  14. Review
  15. Review
  16. Review
  17. Mutations inmBio · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shabnam Sharifzadeh
Felix DempwolffDepartment of Biology, Indiana University, Bloomington, Indiana 47405, United States.
Daniel B KearnsDepartment of Biology, Indiana University, Bloomington, Indiana 47405, United States.
Indiana University Bloomington · USUniversity of Minnesota · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Douglas Yee · 1998 to 2026
$100.4M
Swarming motility and the regulation of flagellar biosynthesis in Bacillus subtilisR35GM131783 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Daniel B Kearns · 2019 to 2026
$3.9M
Targeted natural product diversification to identify novel antibacterial agentsDP2OD008592 · OD · UNIVERSITY OF MINNESOTA · PI CARLSON, ERIN ELIZABETH · 2011 to 2011
$2.2M
Spaciotemporal Regulation of Specific Penicillin Binding Protein (PBP) Function Determined by New Activity-Based ApproachesR01GM128439 · NIGMS · UNIVERSITY OF MINNESOTA · PI CARLSON, ERIN ELIZABETH, WINKLER, MALCOLM E. · 2018 to 2019
$936k
NCI NIH HHS P30 CA077598NIGMS NIH HHS R01 GM128439NIGMS NIH HHS R35 GM131783NIH HHS DP2 OD008592
6 · The paper itself

Abstract

Selective chemical probes enable individual investigation of penicillin-binding proteins (PBPs) and provide critical information about their enzymatic activity with spatial and temporal resolution. To identify scaffolds for novel probes to study peptidoglycan biosynthesis in

Indexed as

AcetylglucosamineAnti-Bacterial AgentsBacillus subtilisbeta-LactamsCell DivisionCell ProliferationDrug Evaluation, PreclinicalEnzyme ActivationEnzyme InhibitorsFluorescent DyesGlycosylationHumansLightingMuramic AcidsOptical ImagingPenicillin-Binding ProteinsAcetylglucosamineAnti-Bacterial Agentsbeta-LactamsEnzyme InhibitorsFluorescent DyesMuramic AcidsN-acetylmuramic acidPenicillin-Binding Proteins

Identifiers

PMID32155044
PMCPMC7784776
OpenAlexW3012515310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.