Evidence map›Paper›PMID 32154840›Full record

ArticleBrain : a journal of neurology2020

Reply: The repeat variant in MSH3 is not a genetic modifier for spinocerebellar ataxia type 3 and Friedreich's ataxia.

Michael Flower, Vilija Lomeikaite, Peter Holmans, Lesley Jones, Sarah J Tabrizi, Darren G Monckton

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in Brain : a journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Michael FlowerDepartment of Neurodegenerative Disease and Dementia Research Institute, UCL, UK.
Vilija LomeikaiteInstitute of Molecular, Cell and Systems Biology, University of Glasgow, UK.
Peter HolmansMRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK.
Lesley JonesMRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK.
Sarah J TabriziDepartment of Neurodegenerative Disease and Dementia Research Institute, UCL, UK.
Darren G MoncktonInstitute of Molecular, Cell and Systems Biology, University of Glasgow, UK.

Funding

Medical Research Council MR/L010305/1Medical Research Council MR/N028767/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Friedreich AtaxiaMachado-Joseph DiseaseMyotonic DystrophyHumansMutS Homolog 3 ProteinPhenotypeTrinucleotide RepeatsMSH3 protein, humanMutS Homolog 3 Protein

Identifiers

PMID32154840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.