Evidence map›Paper›PMID 32154648›Full record

ReviewJournal of cellular and molecular medicine2020

Gadolinium-containing carbon nanomaterials for magnetic resonance imaging: Trends and challenges.

Andrés Rodríguez-Galván, Margarita Rivera, Patricia García-López, Luis A Medina, Vladimir A Basiuk

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Synthesis and characterization of GdScientific reports · 2023
    Article
  8. Review
  9. Future Prospects for Clinical Applications of Nanocarbons Focusing on Carbon Nanotubes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrés Rodríguez-GalvánUnidad de Investigación Biomédica en Cáncer INCan-UNAM, Instituto Nacional de Cancerología, Ciudad de Méxi, Mexico.ORCID 0000-0001-7208-773X
Margarita RiveraInstituto de Física, Universidad Nacional Autónoma de México, Coyoacán, Ciudad de México, Mexico.
Patricia García-LópezLaboratorio de Farmacología, Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Ciudad de México, Mexico.
Luis A MedinaUnidad de Investigación Biomédica en Cáncer INCan-UNAM, Instituto Nacional de Cancerología, Ciudad de Méxi, Mexico.
Vladimir A BasiukInstituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.ORCID 0000-0001-7864-9203

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gadolinium-containing carbon nanomaterials are a new class of contrast agent for magnetic resonance imaging. They are characterized by a superior proton relaxivity to any current commercial gadolinium contrast agent and offer the possibility to design multifunctional contrasts. Intense efforts have been made to develop these nanomaterials because of their potential for better results than the available gadolinium contrast agents. The aim of the present work is to provide a review of the advances in research on gadolinium-containing carbon nanomaterials and their advantages over conventional gadolinium contrast agents. Due to their enhanced proton relaxivity, they can provide a reliable imaging contrast for cells, tissues or organs with much smaller doses than currently used in clinical practice, thus leading to reduced toxicity (as shown by cytotoxicity and biodistribution studies). Their active targeting capability allows for improved MRI of molecular or cellular targets, overcoming the limited labelling capability of available contrast agents (restricted to physiological irregularities during pathological conditions). Their potential of multifunctionality encompasses multimodal imaging and the combination of imaging and therapy.

Indexed as

CarbonContrast MediaGadoliniumHumansMagnetic Resonance ImagingMultimodal ImagingNanostructuresTissue DistributionCarbonContrast MediaGadoliniumbiodistributioncarbon nanomaterialscell labellinggadolinium contrast agentmagnetic resonance imagingmultifunctional contrast agenttoxicity

Identifiers

PMID32154648
PMCPMC7171414

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.