SynthesisThe British journal of surgery2020
Functional complaints and quality of life after transanal total mesorectal excision: a meta-analysis.
Synthesis in The British journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 6 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Is radical surgery always necessary in early rectal cancer? A systematic review of randomised trials.Surgical endoscopy · 2026Pooled it
- Quality of life and functional outcomes after laparoscopic total mesorectal excision (LaTME) and transanal total mesorectal excision (taTME) for rectal cancer. an updated meta-analysis.International journal of colorectal disease · 2024Pooled it
- Functional outcomes and quality of life following open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in rectal cancer patients: a systematic review and meta-analysis.Surgical endoscopy · 2024Pooled it
- Long-term oncologic outcomes of transanal TME compared with transabdominal TME for rectal cancer: a systematic review and meta-analysis.Surgical endoscopy · 2022Pooled it
- Intraoperative neuromonitoring in rectal cancer surgery: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- Comparing functional outcomes between transanal total mesorectal excision (TaTME) and laparoscopic total mesorectal excision (LaTME) for rectal cancer: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- Trial
- Long-term outcomes of pT1 rectal cancer after transanal endoscopic surgery: again, a word of caution on high local recurrence - a cohort study.International journal of colorectal disease · 2026Observational
- Case Report: Rare case of primary rectal adenocarcinoma presenting as a smooth submucosal elevation: endoscopic submucosal excavation and 4 years and 11 months follow-up.Frontiers in medicine · 2026Article
- Short-Course Radiotherapy Combined With CapeOx and PD-1 Inhibitor Following Local Excision in High-Risk Early Rectal Cancer: Study Protocol for a Prospective Phase II Trial (TORCH-LE).Clinical Medicine Insights. Oncology · 2026Article
- Optimal surgical approach for cT3/T4 rectal cancer post-neoadjuvant chemoradiotherapy: robotic surgery versus TaTME guided by superior pelvic diaphragm localization.Journal of robotic surgery · 2025Article
- Bowel-Related Symptoms and Dietary Fiber Intake in Colorectal Cancer Survivors.JAMA network open · 2025Observational
- An In Silico Feasibility Study of Dose-Escalated Hypofractionated Proton Therapy for Rectal Cancer.Cancers · 2025Article
- Anorectal and urogenital functional outcome after robotic and transanal total mesorectal excision for rectal cancer: a propensity score-matched analysis.Techniques in coloproctology · 2025Article
- Does transanal total mesorectal excision (taTME) result in better quality of life and functional outcomes than traditional TME does? A retrospective propensity score-adjusted cohort study.Langenbeck's archives of surgery · 2025Observational
- Three-dimensional heterogeneity of smooth muscle fiber density anterior to the rectum in males: quantitative analysis with implications for transanal total mesorectal excision.International journal of colorectal disease · 2025Article
- Comparative efficacy analysis of laparoscopic-assisted transanal total mesorectal excisionWorld journal of gastrointestinal surgery · 2025Article
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- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTotal mesorectal excision (TME) gives excellent oncological results in rectal cancer treatment, but patients may experience functional problems. A novel approach to performing TME is by single-port transanal minimally invasive surgery. This systematic review evaluated the functional outcomes and quality of life after transanal and laparoscopic TME.
methodsA comprehensive search in PubMed, the Cochrane Library, Embase and the trial registers was conducted in May 2019. PRISMA guidelines were used. Data for meta-analysis were pooled using a random-effects model.
resultsA total of 11 660 studies were identified, from which 14 studies and six conference abstracts involving 846 patients (599 transanal TME, 247 laparoscopic TME) were included. A substantial number of patients experienced functional problems consistent with low anterior resection syndrome (LARS). Meta-analysis found no significant difference in major LARS between the two approaches (risk ratio 1·13, 95 per cent c.i. 0·94 to 1·35; P = 0·18). However, major heterogeneity was present in the studies together with poor reporting of functional baseline assessment.
conclusionNo differences in function were observed between transanal and laparoscopic TME.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.