Evidence map›Paper›PMID 32154498›Full record

ArticleCurrent developments in nutrition2019

Hepatic Cystathionine β-Synthase Activity Is Increased by Greater Postruminal Supply of Met during the Periparturient Period in Dairy Cows.

Mario Vailati-Riboni, Fernanda Batistel, Rainie R C S Yambao, Claudia Parys, Yuan-Xiang Pan, Juan J Loor

Open access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mario Vailati-RiboniDepartment of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA.
Fernanda BatistelDepartment of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA.
Rainie R C S YambaoDepartment of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA.
Claudia ParysEvonik Nutrition & Care GmbH, Hanau-Wolfgang, Germany.
Yuan-Xiang PanDepartment of Food Science and Human Nutrition and Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA.ORCID 0000-0003-3219-4367
Juan J LoorDepartment of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA.ORCID 0000-0003-1586-4365
University of Illinois Urbana-Champaign · USEvonik (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostruminal supply of Met during the periparturient period enhances production efficiency (feed conversion to milk) in dairy cows partly through alleviation of oxidant and inflammatory status. Whether alterations in hepatic 1-carbon metabolism (major contributor of antioxidants) and/or energy metabolism contribute to these beneficial effects is unknown.

objectivesTo investigate alterations in hepatic 1-carbon and energy metabolism and associations with plasma amino acids (AAs) and production efficiency in response to enhanced postruminal supply of Met.

methodsHolstein cows (

resultsCows in the MET group had greater overall (27%,

conclusionsGreater activity of CBS in response to enhanced postruminal supply of Met likely contributes to alleviating oxidant status by increasing concentrations of glutathione. Hence, transsulfuration plays an important role in the observed improvements in production efficiency of dairy cows during the periparturient period.

Indexed as

1-carbon metabolismamino acidslactation; methyl donors; nutrition

Identifiers

PMID32154498
PMCPMC7053581
OpenAlexW2988375686

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.