Evidence map›Paper›PMID 32154497›Full record

ArticleCurrent developments in nutrition2019

Assessment of Acute Serum Iron, Non-Transferrin-Bound Iron, and Gastrointestinal Symptoms with 3-Week Consumption of Iron-Enriched

Amanda E Bries, Chong Wang, Isaac Agbemafle, Brian Wels, Manju B Reddy

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04018300 (Assessment of Gastrointestinal Symptoms and Other Side Effects After Three Week Oral Ferrous Sulfate and Iron-enriched Aspergillus Oryzae Supplementation in Young Female Subjects), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04018300 nacompletednot on this map

Assessment of Gastrointestinal Symptoms and Other Side Effects After Three Week Oral Ferrous Sulfate and Iron-enriched Aspergillus Oryzae Supplementation in Young Female Subjects

TypeinterventionalSponsorIowa State UniversityRan2018 to 2018Enrolled17ConditionsIron Deficiency Anemia, Iron OverloadArmsFerrous sulfate, Aspiron, Placebo
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Scientific opinion on the tolerable upper intake level for iron.EFSA journal. European Food Safety Authority · 2024
    Article
  5. Iron-enrichedThe British journal of nutrition · 2023
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amanda E BriesDepartment of Food Sciences and Human Nutrition, Iowa State University, Ames, IA, USA.
Chong WangDepartment of Statistics, Iowa State University, Ames, IA, USA.
Isaac AgbemafleDepartment of Food Sciences and Human Nutrition, Iowa State University, Ames, IA, USA.
Brian WelsState Hygienic Laboratory, University of Iowa, Ankeny, IA, USA.
Manju B ReddyDepartment of Food Sciences and Human Nutrition, Iowa State University, Ames, IA, USA.
Iowa State University · USUniversity of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIron deficiency anemia (IDA) is a widespread nutritional deficiency, and iron supplementation, especially with ferrous sulfate (FeSO

objectivesThe main objective of this study was to assess the safety of consuming ULT in terms of increasing non-transferrin-bound iron (NTBI) and gastrointestinal distress.

methodsYoung female participants (

resultsSI, %TS, and NTBI were all markedly higher during hours 2-8 (

conclusionsLow NTBI production and fewer common gastrointestinal side effects with ULT suggest that it is a safe oral iron supplement to treat IDA. This trial was registered at clinicaltrials.gov as NCT04018300.

Indexed as

Aspergillus oryzaeferrous sulfategastrointestinal side effectsiron supplementationnon-transferrin-bound ironoxidative stressserum iron

Identifiers

PMID32154497
PMCPMC7053575
OpenAlexW2986863473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.