Evidence map›Paper›PMID 32154391›Full record

ArticleBiochemistry and biophysics reports2020

Creatine kinase/α-crystallin interaction functions in cataract development.

Paul D Hamilton, Stephanie L Bozeman, Usha P Andley

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paul D HamiltonDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Stephanie L BozemanDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Usha P AndleyDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Funding

WASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Philip Raymond Williams · 1985 to 2026
$18.4M
ROLE OF OXYGEN IN OCULAR PATHOLOGYR01EY005681 · NEI · WASHINGTON UNIVERSITY · PI ANDLEY, USHA P · 1985 to 2018
$7.3M
NEI NIH HHS P30 EY002687NEI NIH HHS R01 EY005681
6 · The paper itself

Abstract

Creatine kinase (CK) is an energy storage enzyme that plays an important role in energy metabolism. CK/phosphocreatine functions as an energy buffer and links ATP production sites with ATP utilization sites. Several key mutations in the αA-crystallin (

Indexed as

CataractCKB, creatine kinase BCK, creatine kinaseCKM, creatine kinase MComplex formationCreatine kinasecryaa-R49C, αA-crystallin R49C mutantELISA, enzyme-linked immunosorbent assayGPC, gel permeation chromatographyITC, isothermal titration calorimetryMouse modelPBS, phosphate-buffered salineRALS, right angle light scatteringRI, refractive indexWT, wild-typeα-Crystallin

Identifiers

PMID32154391
PMCPMC7052508
OpenAlexW3007118769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.