Evidence map›Paper›PMID 32154330›Full record

ArticleBio-protocol2019

Analyzing the Functionality of Non-native Hsp70 Proteins in

Laura E Knighton, Lizbeth P Saa, Adam M Reitzel, Andrew W Truman

Open access · bronzeAbstract read
In one paragraph

Article in Bio-protocol, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laura E KnightonDepartment of Biological Sciences, The University of North Carolina at Charlotte, Charlotte, USA.
Lizbeth P SaaDepartment of Biological Sciences, The University of North Carolina at Charlotte, Charlotte, USA.
Adam M ReitzelDepartment of Biological Sciences, The University of North Carolina at Charlotte, Charlotte, USA.
Andrew W TrumanDepartment of Biological Sciences, The University of North Carolina at Charlotte, Charlotte, USA.
University of North Carolina at Charlotte · US

Funding

Regulation of Hsp70-Mediated Cyclin D1 Destruction in Breast CancerR15CA208773 · NCI · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI TRUMAN, ANDREW WILLIAM · 2017 to 2017
$440k
NCI NIH HHS R15 CA208773
6 · The paper itself

Abstract

Yeast are an ideal system to study Heat Shock Protein 70 (Hsp70) function in a cellular context. This protocol was generated to analyze the function of non-native Hsp70 proteins by expressing them as the sole cytosolic Hsp70 in yeast. As an initial step, Hsp70 variants (such as Ssa1 point mutants and non-yeast versions such as

Indexed as

Hsp70Molecular chaperonesNematostellaPlasmid swap

Identifiers

PMID32154330
PMCPMC7062368
OpenAlexW2979227170

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.