Evidence map›Paper›PMID 32154279›Full record

ReviewFrontiers in veterinary science2020

Progress Toward Development of Effective and Safe African Swine Fever Virus Vaccines.

Huldah Sang, Gabrielle Miller, Shehnaz Lokhandwala, Neha Sangewar, Suryakant D Waghela, Richard P Bishop, Waithaka Mwangi

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Recent progress and major gaps in the vaccine development for African swine fever.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. African swine fever virus I73R is a critical virulence-related gene: A potential target for attenuation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
  18. Vaccines for African swine fever: an update.Frontiers in microbiology · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Huldah SangDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, United States.
Gabrielle MillerDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, United States.
Shehnaz LokhandwalaDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, United States.
Neha SangewarDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, United States.
Suryakant D WaghelaDepartment of Veterinary Pathobiology, Texas A&M University, College Station, TX, United States.
Richard P BishopDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States.
Waithaka MwangiDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, United States.
Kansas State University · USTexas A&M University · USWashington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African swine fever is a major concern due to its negative impact on pork production in affected regions. Due to lack of treatment and a safe vaccine, it has been extremely difficult to control this devastating disease. The mechanisms of virus entry, replication within the host cells, immune evasion mechanisms, correlates of protection, and antigens that are effective at inducing host immune response, are now gradually being identified. This information is required for rational design of novel disease control strategies. Pigs which recover from infection with less virulent ASFV isolates can be protected from challenge with related virulent isolates. This strongly indicates that an effective vaccine against ASFV could be developed. Nonetheless, it is clear that effective immunity depends on both antibody and cellular immune responses. This review paper summarizes the key studies that have evaluated three major approaches for development of African Swine Fever virus vaccines. Recent immunization strategies have involved development and

Indexed as

ASFattenuated viruslive vectorsubunit vaccinevaccine

Identifiers

PMID32154279
PMCPMC7047163
OpenAlexW3007846511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.