ArticleFrontiers in medicine2020
Comparison of Early vs. Delayed Anakinra Treatment in Patients With Adult Onset Still's Disease and Effect on Clinical and Laboratory Outcomes.
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In one paragraph
Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 29 citations in OpenAlex.
- Methotrexate in Still's Disease: An Updated Perspective on Efficacy and Safety.Advances in therapy · 2026Review
- Association between canakinumab dose and long-term remission in Still's disease: insights from the AIDA network registry.Frontiers in pharmacology · 2026Article
- Anakinra in the management of adult-onset still's disease: a single-center experience.Internal and emergency medicine · 2025Article
- Diagnosing and Treating Systemic Juvenile Idiopathic Arthritis and Adult-Onset Still's Disease as Part of the Still's Disease Continuum.Mediterranean journal of rheumatology · 2024Review
- From Bench to Bedside in Rheumatoid Arthritis from the "2022 GISEA International Symposium".Journal of clinical medicine · 2023Review
- Efficacy of canakinumab in patients with Still's disease across different lines of biologic therapy: real-life data from the International AIDA Network Registry for Still's Disease.Frontiers in medicine · 2023Article
- Canakinumab as first-line biological therapy in Still's disease and differences between the systemic and the chronic-articular courses: Real-life experience from the international AIDA registry.Frontiers in medicine · 2022Article
- Adult-onset Still's disease: A disease at the crossroad of innate immunity and autoimmunity.Frontiers in medicine · 2022Review
- Interleukin-1 Blockade in Polygenic Autoinflammatory Disorders: Where Are We now?Frontiers in pharmacology · 2020Review
- Repurposing of Biologic and Targeted Synthetic Anti-Rheumatic Drugs in COVID-19 and Hyper-Inflammation: A Comprehensive Review of Available and Emerging Evidence at the Peak of the Pandemic.Frontiers in pharmacology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
50 authors at 17 institutions in 1 country.
Antonio VitaleResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.
Giulio CavalliDepartment of General and Specialized Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Piero RuscittiDivision of Rheumatology, Department of Biotechnological and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.
Jurgen SotaResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.
Serena ColafrancescoRheumatology Unit, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy.
Roberta PrioriRheumatology Unit, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy.
Guido ValesiniRheumatology Unit, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy.
Lorenza Maria ArgoliniDivision of Rheumatology, ASST Gaetano Pini, Milan, Italy.
Elena BaldisseraUnit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Elena BartoloniRheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.
Daniele CammelliDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Giovanni CanestrariInstitute of Rheumatology and Affine Sciences, Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy.
Elena CavallaroDepartment of Medical and Biological Sciences, Rheumatology Clinic, University of Udine, Udine, Italy.
Maria Grazia MassaroPeriodic Fever Research Center, Institute of Internal Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Rome, Italy.
Paola CiprianiDivision of Rheumatology, Department of Biotechnological and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.
Ginevra De MarchiDepartment of Medical and Biological Sciences, Rheumatology Clinic, University of Udine, Udine, Italy.
Salvatore De VitaDepartment of Medical and Biological Sciences, Rheumatology Clinic, University of Udine, Udine, Italy.
Giacomo EmmiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Micol FrassiRheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Roberto GerliRheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.
Elisa GremeseInstitute of Rheumatology and Affine Sciences, Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy.
Florenzo IannoneRheumatology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Marco FornaroRheumatology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Anna PaladiniResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.
Giuseppe LopalcoRheumatology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Raffaele MannaPeriodic Fever Research Center, Institute of Internal Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico A. Gemelli, Rome, Italy.
Alessandro MathieuRheumatology Unit, Department of Medical Sciences, University and AOU of Cagliari, Cagliari, Italy.
Carlomaurizio MontecuccoDepartment of Rheumatology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.
Marta MoscaRheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Ilaria PiazzaRheumatology Unit, Department of Medicine, University of Verona, Verona, Italy.
Matteo PigaRheumatology Unit, Department of Medical Sciences, University and AOU of Cagliari, Cagliari, Italy.
Irene PontikakiDivision of Rheumatology, ASST Gaetano Pini, Milan, Italy.
Micol RomanoDivision of Rheumatology, ASST Gaetano Pini, Milan, Italy.
Silvia RossiDepartment of Rheumatology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.
Maurizio RossiniRheumatology Unit, Department of Medicine, University of Verona, Verona, Italy.
Elena SilvestriDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Chiara StagnaroRheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Rosaria TalaricoRheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Bruno FredianiResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.
Angela TincaniRheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Ombretta ViapianaRheumatology Unit, Department of Medicine, University of Verona, Verona, Italy.
Gianfranco VitielloDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Paola GalozziDepartment of Medicine DIMED, Rheumatology Unit, University of Padua, Padua, Italy.
Paolo SfrisoDepartment of Medicine DIMED, Rheumatology Unit, University of Padua, Padua, Italy.
Carla GaggianoClinical Pediatrics, Department of Molecular Medicine and Development, University of Siena, Siena, Italy.
Salvatore GrossoClinical Pediatrics, Department of Molecular Medicine and Development, University of Siena, Siena, Italy.
Donato RiganteInstitute of Pediatrics, Università Cattolica Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Lorenzo DagnaDepartment of General and Specialized Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Roberto GiacomelliDivision of Rheumatology, Department of Biotechnological and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.
Luca CantariniResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.
University of Siena · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Florence · ITIstituto Ortopedico Gaetano Pini · ITSapienza University of Rome · ITUniversity of Bari Aldo Moro · ITUniversity of L'Aquila · ITUniversity of Pisa · ITUniversity of Udine · ITUniversity of Verona · ITUniversity of Brescia · ITUniversity of Cagliari · ITUniversity of Padua · ITUniversity of Pavia · ITUniversity of Perugia · ITVita-Salute San Raffaele University · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
adult onset Still's diseaseanakinraautoinflammatory diseasesinnovative biotechnologiesinterleukin-1personalized medicinesystemic onset juvenile idiopathic arthritistreat to target
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.