Evidence map›Paper›PMID 32154254›Full record

ArticleFrontiers in medicine2020

Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of

Jie Feng, Jacob Leone, Sunjya Schweig, Ying Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Article
  3. Antiviral Activity of Water-Alcoholic Extract ofInternational journal of molecular sciences · 2025
    Article
  4. Bacterial persisters: molecular mechanisms and therapeutic development.Signal transduction and targeted therapy · 2024
    Review
  5. Frontiers in cellular and infection microbiology · 2024
    Article
  6. Artemisinin as a therapeuticNatural product reports · 2023
    Review
  7. Review
  8. Molecules (Basel, Switzerland) · 2023
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Extraction and Fractionation of Bioactives fromPharmaceuticals (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Life (Basel, Switzerland) · 2021
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jie FengDepartment of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Jacob LeoneFOCUS Health Group, Naturopathic, Novato, CA, United States.
Sunjya SchweigCalifornia Center for Functional Medicine, Kensington, CA, United States.
Ying ZhangDepartment of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lyme disease is the most common vector-borne disease in the US and Europe. Although the current recommended Lyme antibiotic treatment is effective for the majority of Lyme disease patients, about 10-20% of patients continue to suffer from persisting symptoms. There have been various anecdotal reports on the use of herbal extracts for treating patients with persisting symptoms with varying degree of improvements. However, it is unclear whether the effect of the herb products is due to their direct antimicrobial activity or their effect on host immune system. In the present study, we investigated the antimicrobial effects of 12 commonly used botanical medicines and three other natural antimicrobial agents for potential anti-

Indexed as

antimicrobial activitybiofilmBorrelia burgdorferibotanical medicinesherbsLyme diseasenatural medicinespersisters

Identifiers

PMID32154254
PMCPMC7050641
OpenAlexW3008531079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.