Evidence map›Paper›PMID 32154238›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Antioxidant Nanoparticles for Concerted Inhibition of α-Synuclein Fibrillization, and Attenuation of Microglial Intracellular Aggregation and Activation.

Nanxia Zhao, Xue Yang, Hannah R Calvelli, Yue Cao, Nicola L Francis, Rebecca A Chmielowski, Laurie B Joseph, Zhiping P Pang, Kathryn E Uhrich, Jean Baum and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
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  3. Article
  4. Nanomedicines Against Mitochondrial Dysfunction-Induced Metabolic Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
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  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Nanoparticle-based Gene Therapy for Neurodegenerative Disorders.Mini reviews in medicinal chemistry · 2024
    Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Impact of dietary polyphenols on neuroinflammation-associated disorders.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Nanxia ZhaoDepartment of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, United States.
Xue YangDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ, United States.
Hannah R CalvelliDepartment of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ, United States.
Yue CaoDepartment of Chemistry, University of California, Riverside, Riverside, CA, United States.
Nicola L FrancisDepartment of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, United States.
Rebecca A ChmielowskiDepartment of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, United States.
Laurie B JosephDepartment of Pharmacology and Toxicology, Rutgers, The State University of New Jersey, Piscataway, NJ, United States.
Zhiping P PangDepartment of Neuroscience and Cell Biology, Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States.
Kathryn E UhrichDepartment of Chemistry, University of California, Riverside, Riverside, CA, United States.
Jean BaumDepartment of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ, United States.
Prabhas V MogheDepartment of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, United States.
Rutgers, The State University of New Jersey · USUniversity of California, Riverside · US

Funding

UMDNJ/Rutgers University CounterACT Research Center of ExcellenceU54AR055073 · NIAMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI HECK, DIANE E · 2006 to 2024
$71.4M
Microglial-Targeted Nanotherapeutics for Inhibition of Alpha-Synuclein Aggregation and Inflammation in Neurodegenerative DiseasesR21AG060024 · NIA · RUTGERS, THE STATE UNIV OF N.J. · PI MOGHE, PRABHAS V, PANG, ZHIPING P. · 2018 to 2019
$435k
Nanofibrous Scaffolds for Transplantation of Human Dopaminergic NeuronsR21NS095082 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI MOGHE, PRABHAS V, PANG, ZHIPING P. · 2015 to 2016
$424k
NIAMS NIH HHS U54 AR055073NIA NIH HHS R21 AG060024NINDS NIH HHS R21 NS095082
6 · The paper itself

Abstract

Parkinson's Disease is characterized by the loss of dopaminergic neurons in the

Indexed as

alpha synucleinferulic acidmicrogliananomedicineParkinson’s diseasetannic acid

Identifiers

PMID32154238
PMCPMC7046761
OpenAlexW3007880325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.