Evidence map›Paper›PMID 32154210›Full record

ArticleFrontiers in chemistry2020

Wet-Spun Trojan Horse Cell Constructs for Engineering Muscle.

Anita F Quigley, Rhys Cornock, Tharun Mysore, Javad Foroughi, Magdalena Kita, Joselito M Razal, Jeremy Crook, Simon E Moulton, Gordon G Wallace, Robert M I Kapsa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Anita F QuigleyARC Centre for Electromaterials Science, Intelligent Polymer Research Institute, University of Wollongong, Fairy Meadow, NSW, Australia.
Rhys CornockARC Centre for Electromaterials Science, Intelligent Polymer Research Institute, University of Wollongong, Fairy Meadow, NSW, Australia.
Tharun MysoreSchool of Medicine and Faculty of Health, Deakin University, Waurn Ponds, VIC, Australia.
Javad ForoughiARC Centre for Electromaterials Science, Intelligent Polymer Research Institute, University of Wollongong, Fairy Meadow, NSW, Australia.
Magdalena KitaARC Centre for Electromaterials Science, Intelligent Polymer Research Institute, University of Wollongong, Fairy Meadow, NSW, Australia.
Joselito M RazalInstitute for Frontier Materials, Deakin University, Waurn Ponds, VIC, Australia.
Jeremy CrookARC Centre for Electromaterials Science, Intelligent Polymer Research Institute, University of Wollongong, Fairy Meadow, NSW, Australia.
Simon E MoultonDepartment of Biomedical Engineering, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, VIC, Australia.
Gordon G WallaceARC Centre for Electromaterials Science, Intelligent Polymer Research Institute, University of Wollongong, Fairy Meadow, NSW, Australia.
Robert M I KapsaARC Centre for Electromaterials Science, Intelligent Polymer Research Institute, University of Wollongong, Fairy Meadow, NSW, Australia.
ARC Centre of Excellence for Electromaterials Science · AUUniversity of Wollongong · AUDeakin University · AUSt Vincent's Hospital · AUSwinburne University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Engineering of 3D regenerative skeletal muscle tissue constructs (skMTCs) using hydrogels containing muscle precursor cells (MPCs) is of potential benefit for repairing Volumetric Muscle Loss (VML) arising from trauma (e.g., road/industrial accident, war injury) or for restoration of functional muscle mass in disease (e.g., Muscular Dystrophy, muscle atrophy). Additive Biofabrication (AdBiofab) technologies make possible fabrication of 3D regenerative skMTCs that can be tailored to specific delivery requirements of VML or functional muscle restoration. Whilst 3D printing is useful for printing constructs of many tissue types, the necessity of a balanced compromise between cell type, required construct size and material/fabrication process cyto-compatibility can make the choice of 3D printing a secondary alternative to other biofabrication methods such as wet-spinning. Alternatively, wet-spinning is more amenable to formation of fibers rather than (small) layered 3D-Printed constructs. This study describes the fabrication of biosynthetic alginate fibers containing MPCs and their use for delivery of dystrophin-expressing cells to dystrophic muscle in the

Indexed as

alginate fibersbiosynthetic muscle scaffoldmuscle engineeringmyoblastswet-spun

Identifiers

PMID32154210
PMCPMC7044405
OpenAlexW3007382678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.