Evidence map›Paper›PMID 32154168›Full record

ArticleFrontiers in oncology2020

Fully-Automated Segmentation of Nasopharyngeal Carcinoma on Dual-Sequence MRI Using Convolutional Neural Networks.

Yufeng Ye, Zongyou Cai, Bin Huang, Yan He, Ping Zeng, Guorong Zou, Wei Deng, Hanwei Chen, Bingsheng Huang

Abstract read
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Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

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0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yufeng YeDepartment of Radiology, Panyu Central Hospital, Guangzhou, China.
Zongyou CaiMedical AI Lab, School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, China.
Bin HuangMedical AI Lab, School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, China.
Yan HeDepartment of Oncology, Panyu Central Hospital, Guangzhou, China.
Ping ZengDepartment of Radiology, Shenzhen University General Hospital, Shenzhen, China.
Guorong ZouDepartment of Oncology, Panyu Central Hospital, Guangzhou, China.
Wei DengDepartment of Radiology, Panyu Central Hospital, Guangzhou, China.
Hanwei ChenDepartment of Radiology, Panyu Central Hospital, Guangzhou, China.
Bingsheng HuangMedical Imaging Institute of Panyu, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we proposed an automated method based on convolutional neural network (CNN) for nasopharyngeal carcinoma (NPC) segmentation on dual-sequence magnetic resonance imaging (MRI). T1-weighted (T1W) and T2-weighted (T2W) MRI images were collected from 44 NPC patients. We developed a dense connectivity embedding U-net (DEU) and trained the network based on the two-dimensional dual-sequence MRI images in the training dataset and applied post-processing to remove the false positive results. In order to justify the effectiveness of dual-sequence MRI images, we performed an experiment with different inputs in eight randomly selected patients. We evaluated DEU's performance by using a 10-fold cross-validation strategy and compared the results with the previous studies. The Dice similarity coefficient (DSC) of the method using only T1W, only T2W and dual-sequence of 10-fold cross-validation as different inputs were 0.620 ± 0.0642, 0.642 ± 0.118 and 0.721 ± 0.036, respectively. The median DSC in 10-fold cross-validation experiment with DEU was 0.735. The average DSC of seven external subjects was 0.87. To summarize, we successfully proposed and verified a fully automatic NPC segmentation method based on DEU and dual-sequence MRI images with accurate and stable performance. If further verified, our proposed method would be of use in clinical practice of NPC.

Indexed as

convolutional neural networksdual-sequencemagnetic resonance imagenasopharyngeal carcinomasegmentation

Identifiers

PMID32154168
PMCPMC7045897

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.