Evidence map›Paper›PMID 32154124›Full record

ArticleSchizophrenia research. Cognition2020

False memory production in schizophrenia: A neurophysiological investigation.

Grégoire Favre, Sibylle K Horat, François R Herrmann, Isabelle Gothuey, Joseph Ventura, Marco C G Merlo, Pascal Missonnier

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Article in Schizophrenia research. Cognition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Grégoire FavreLaboratory for Psychiatric Neuroscience and Psychotherapy, Department of Medicine, Faculty of Science & Medicine, University of Fribourg, Chemin du Musée 5, CH 1700 Fribourg, Switzerland.
Sibylle K HoratLaboratory for Psychiatric Neuroscience and Psychotherapy, Department of Medicine, Faculty of Science & Medicine, University of Fribourg, Chemin du Musée 5, CH 1700 Fribourg, Switzerland.
François R HerrmannDivision of geriatrics, Department of rehabilitation and geriatrics, Geneva University Hospitals and University of Geneva, CH 1226 Thônex, Switzerland.
Isabelle GothueyMental Health Network Fribourg (RFSM), Sector of psychiatry and psychotherapy for adults, L'Hôpital 140, Case postale 90, CH 1633 Marsens, Switzerland.
Joseph VenturaDepartment of Psychiatry and Biobehavioural Sciences, University of California, Los Angeles, CA, United States.
Marco C G MerloLaboratory for Psychiatric Neuroscience and Psychotherapy, Department of Medicine, Faculty of Science & Medicine, University of Fribourg, Chemin du Musée 5, CH 1700 Fribourg, Switzerland.
Pascal MissonnierLaboratory for Psychiatric Neuroscience and Psychotherapy, Department of Medicine, Faculty of Science & Medicine, University of Fribourg, Chemin du Musée 5, CH 1700 Fribourg, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe topic of false memory in schizophrenia has been well documented in earlier research contributions. To date, there is no study exploring the implications of specific neural networks during this phenomenon in patients suffering from schizophrenia.

methodsWe compared 17 patients suffering from psychosis (SCZ) to 33 healthy controls (HC) performing a verbal memory task designed to produce false memories, i.e. the Deese-Roediger-McDermott paradigm (DRM). Electroencephalography was used to specifically analyze the P2 and N400 event-related potentials components.

resultsThe SCZ patients showed a reduced ability to distinguish between true and false memories as assessed by the A' index which was calculated based on the false and true memory rates. The morphology of the P2 differed in frontal electrode region with a lower amplitude in SCZ. In addition, the amplitude of N400 was more pronounced (more negative) in HC than in SCZ in centro-parietal electrode site.

conclusionsWe suggest that the differences found in P2 amplitude are associated with difficulties of SCZ patients to efficiently compare item-specific features of a mnesic elements to incoming stimuli which impair the subsequent verbal memory information processing reflected by the N400 component amplitude decrease. These results are consistent with the idea that SCZ use a different strategy while they perform the DRM paradigm.

Indexed as

Event-related potentials (ERPs)False memoriesSchizophrenia

Identifiers

PMID32154124
PMCPMC7052439

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.