Evidence map›Paper›PMID 32154064›Full record

ArticleCurrent behavioral neuroscience reports2019

Gradient theories of brain activation: A novel application to studying the parental brain.

Helena J V Rutherford, Jiansong Xu, Patrick D Worhunsky, Rubin Zhang, Sarah W Yip, Kristen P Morie, Vince D Calhoun, Sohye Kim, Lane Strathearn, Linda C Mayes and 1 more

Open access · greenAbstract read
In one paragraph

Article in Current behavioral neuroscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Helena J V RutherfordChild Study Center, Yale University School of Medicine, New Haven, CT 06510, United States.
Jiansong XuDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States.
Patrick D WorhunskyDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States.
Rubin ZhangDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States.
Sarah W YipDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States.
Kristen P MorieDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States.
Vince D CalhounDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States.
Sohye KimDepartment of Obstetrics and Gynecology, Baylor College of Medicine.
Lane StrathearnDepartment of Pediatrics and Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine.
Linda C MayesChild Study Center, Yale University School of Medicine, New Haven, CT 06510, United States.
Marc N PotenzaChild Study Center, Yale University School of Medicine, New Haven, CT 06510, United States.
Yale University · USBaylor College of Medicine · US

Funding

Transcranial Direct Current Stimulation for Treatment of Auditory Verbal HalluciP20GM103472 · NIGMS · THE MIND RESEARCH NETWORK · PI BEDRICK, EDWARD J · 2012 to 2017
$14.3M
Multivariate methods for identifying multitask/multimodal brain imaging biomarkersR01EB006841 · NIBIB · THE MIND RESEARCH NETWORK · PI VINCE D CALHOUN, Sergey Plis · 2007 to 2026
$9.8M
Oxytocin and Brain Reward and Stress Responses to Infant Cues in Addicted MothersR01DA026437 · NIDA · UNIVERSITY OF IOWA · PI MAYES, LINDA CAROL, STRATHEARN, LANE · 2010 to 2020
$7.2M
REGULATION OF AROUSAL AND ATTENTION IN COCAINE EXPOSEDR01DA006025 · NIDA · YALE UNIVERSITY · PI MAYES, LINDA CAROL · 1992 to 2007
$6.0M
Male/Female differences in psychosis and mood disorders:Dynamic imaging-genomic models for characterizing and predicting psychosis and mood dR01MH118695 · NIMH · GEORGIA STATE UNIVERSITY · PI ADALI, TULAY, CALHOUN, VINCE D · 2019 to 2023
$3.8M
Unified multivariate data-driven solutions for static and dynamic brain connectivityR01EB020407 · NIBIB · THE MIND RESEARCH NETWORK · PI ADALI, TULAY, CALHOUN, VINCE D · 2015 to 2018
$2.7M
Intranasal Oxytocin: A Neuropharmacological Intervention for Maternal Neglect?R01HD065819 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI STRATHEARN, LANE · 2010 to 2014
$1.2M
Development of Reward Processing in prenatally exposed adolescents and young adultsK01DA042937 · NIDA · YALE UNIVERSITY · PI MORIE, KRISTEN PAULA · 2017 to 2021
$907k
Neural mechanisms of galantamine treatment for cocaine dependenceK01DA039299 · NIDA · YALE UNIVERSITY · PI YIP, SARAH · 2016 to 2020
$905k
Investigation of neurofunctional reorganization in cocaine addiction using mGluR5 PET and fMRIK01DA042998 · NIDA · YALE UNIVERSITY · PI WORHUNSKY, PATRICK D · 2017 to 2021
$900k
Functional networks related to cocaine dependence and its treatment and relapseR01DA039136 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2016 to 2018
$754k
A Functional MRI Study of Mother-Infant AttachmentK23HD043097 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI STRATHEARN, LANE · 2004 to 2008
$675k
NIBIB NIH HHS R01 EB006841NIBIB NIH HHS R01 EB020407NICHD NIH HHS K23 HD043097NICHD NIH HHS R01 HD065819NICHD NIH HHS R03 HD080998NIDA NIH HHS K01 DA039299NIDA NIH HHS K01 DA042937NIDA NIH HHS K01 DA042998NIDA NIH HHS R01 DA006025NIDA NIH HHS R01 DA026437NIDA NIH HHS R01 DA039136NIDA NIH HHS R03 DA045289NIGMS NIH HHS P20 GM103472NIMH NIH HHS R01 MH118695
6 · The paper itself

Abstract

purpose of reviewParental brain research primarily employs general-linear-model-based (GLM-based) analyses to assess blood-oxygenation-level-dependent responses to infant auditory and visual cues, reporting common responses in shared cortical and subcortical structures. However, this approach does not reveal intermixed neural substrates related to different sensory modalities. We consider this notion in studying the parental brain. RECENT

findingsSpatial independent component analysis (sICA) has been used to separate mixed source signals from overlapping functional networks. We explore relative differences between GLM-based analysis and sICA as applied to an fMRI dataset acquired from women while they listened to infant cries or viewed infant sad faces. SUMMARY: There is growing appreciation for the value of moving beyond GLM-based analyses to consider brain functional organization as continuous, distributive, and overlapping gradients of neural substrates related to different sensory modalities. Preliminary findings suggest sICA can be applied to the study of the parental brain.

Indexed as

balanced excitation/inhibitiongeneral linear modelindependent component analysisinfant cueneuroimagingparent brain

Identifiers

PMID32154064
PMCPMC7062306
OpenAlexW2954672341

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.