Evidence map›Paper›PMID 32154010›Full record

ArticleCardio-oncology (London, England)2019

Increased skeletal intermuscular fat is associated with reduced exercise capacity in cancer survivors: a cross-sectional study.

Kerryn W Reding, Peter Brubaker, Ralph D'Agostino, Dalane W Kitzman, Barbara Nicklas, Dale Langford, Michael Grodesky, W Gregory Hundley

Open access · goldAbstract read
In one paragraph

Article in Cardio-oncology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

  1. Muscle quality during cancer treatment and associations with health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Efficacy of exercise interventions for women during and after gynaecological cancer treatment - a systematic scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kerryn W Reding1Department of Biobehavioral Nursing and Health Informatics, University of Washington School of Nursing, Seattle, WA USA.
Peter Brubaker2Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC USA.
Ralph D'Agostino3Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC USA.
Dalane W Kitzman4Department of Internal Medicine (Section on Cardiology), Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1045 USA.
Barbara Nicklas5Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC USA.
Dale Langford6Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, WA USA.
Michael Grodesky7Department of Psychosocial and Community Health, University of Washington School of Nursing, Seattle, WA USA.
W Gregory Hundley4Department of Internal Medicine (Section on Cardiology), Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1045 USA.
Wake Forest University · USUniversity of Washington · USVirginia Commonwealth University · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Preventing Anthracycline Cardiovascular Toxicity with StatinsR01HL118740 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2013 to 2018
$4.2M
Understanding and Predicting Fatigue, CV Decline & Events After Breast CA TreatmentR01CA199167 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2015 to 2022
$3.2M
Early Imaging Detection of CV Injury after CancerR01CA167821 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY, JOLLY, MARIE-PIERRE · 2012 to 2016
$2.5M
NCI NIH HHS P30 CA012197NCI NIH HHS R01 CA167821NCI NIH HHS R01 CA199167NHLBI NIH HHS R01 HL118740
6 · The paper itself

Abstract

backgroundCancer survivors experience on average a 20% reduction in peak exercise capacity (VO METHODS AND

resultsTwenty eight individuals: 14 cancer survivors > 12-months post-cancer treatment and 14 individuals without cancer were matched on age, gender, and body mass index (BMI). Participants underwent magnetic resonance imaging (MRI) assessments of IMF within the paraspinal muscles, VO

conclusionAmong cancer survivors that previously received anthracyclines, increased intermuscular fat is associated with reduced VO

Indexed as

Cancer survivorsExercise intoleranceMuscle composition

Identifiers

PMID32154010
PMCPMC7048042
OpenAlexW2947605652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.