Evidence map›Paper›PMID 32153993›Full record

ArticleRegenerative biomaterials2020

Quantification of rhBMP2 in bioactive bone materials.

Huan Lian, Han Wang, Qianqian Han, Chunren Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Huan LianDivision of Biomaterials, Department of Medical Devices, National Institutes for Food and Drug Control, No. 31 Huatuo Road, Beijing 102629, China.ORCID 0000-0001-8227-9751
Han WangDivision of Biomaterials, Department of Medical Devices, National Institutes for Food and Drug Control, No. 31 Huatuo Road, Beijing 102629, China.
Qianqian HanDivision of Biomaterials, Department of Medical Devices, National Institutes for Food and Drug Control, No. 31 Huatuo Road, Beijing 102629, China.
Chunren WangDivision of Biomaterials, Department of Medical Devices, National Institutes for Food and Drug Control, No. 31 Huatuo Road, Beijing 102629, China.
National Institutes for Food and Drug Control · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone morphogenetic protein (BMP), belongs to transforming growth factor-β (TGF-β) superfamily except BMP-1. Implanting BMP into muscular tissues induces ectopic bone formation at the site of implantation, which provides opportunity for the treatment of bone defects. Recombinant human BMP-2 (rhBMP-2) has been used clinically, but the lack of standard methods for quantifying rhBMP-2 biological activity greatly hindered the progress of commercialization. In this article, we describe an

Indexed as

rhBMP-2 bioactivity quantificationR programmingstatistical model fitting

Identifiers

PMID32153993
PMCPMC7053258
OpenAlexW2995801258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.