Evidence map›Paper›PMID 32153957›Full record

ArticleBMC nutrition2019

Clinical application of invalid foods using mealworms and evaluation of nutrition status and immune function: a study protocol for a randomized, double blind, placebo-controlled trial.

Hyung Sun Kim, Yun Sun Lee, Soo Yun Jang, So Young Jun, Jin Hong Lim, Im Kyung Kim, Hyung Mi Kim, Joon Seong Park

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03201926 (Development and Clinical Application of Invalid Foods Using Mealworms), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03201926 naunknown statusnot on this map

Development and Clinical Application of Invalid Foods Using Mealworms

TypeinterventionalSponsorYonsei UniversityRan2017 to 2020Enrolled168ConditionsPancreatobiliary Disease, Liver DiseaseArmsmealworms, grain powder
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hyung Sun Kim1Pancreatobiliary Cancer Clinic, Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, 20, Eonju-ro 63-gil, Gangnam-gu, Seoul, 06229 Korea.
Yun Sun Lee1Pancreatobiliary Cancer Clinic, Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, 20, Eonju-ro 63-gil, Gangnam-gu, Seoul, 06229 Korea.
Soo Yun Jang2Department of Nutrition and Dietetics, Gangnam Severance Hospital, Yonsei University, Seoul, Korea.
So Young Jun1Pancreatobiliary Cancer Clinic, Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, 20, Eonju-ro 63-gil, Gangnam-gu, Seoul, 06229 Korea.
Jin Hong Lim1Pancreatobiliary Cancer Clinic, Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, 20, Eonju-ro 63-gil, Gangnam-gu, Seoul, 06229 Korea.
Im Kyung Kim3Department of Surgical critical care medicine, Severance Hospital, Yonsei University, Seoul, Korea.
Hyung Mi Kim2Department of Nutrition and Dietetics, Gangnam Severance Hospital, Yonsei University, Seoul, Korea.
Joon Seong Park1Pancreatobiliary Cancer Clinic, Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, 20, Eonju-ro 63-gil, Gangnam-gu, Seoul, 06229 Korea.
Gangnam Severance Hospital · KRYonsei University · KRSeverance Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProtein intake is important for the recovery of the immune system, physical strength, and wound healing after surgery. Sarcopenia is associated with a poor prognosis when compared to patients without sarcopenia in cancer patients. Recently, edible insects, such as mealworms, have been recognized as having a high protein content. In this study, we will evaluate the effect of nutritional status and immune function change based on a patient's ingestion of mealworms after hepatobiliary pancreatic surgery. METHODS/

designThis is a prospective, two-armed, phase III study investigating the effect of mealworm improving nutrition and immune status in patients after hepatobiliary pancreatic surgery. In the trial group, the patients will be provided with mealworms for 2 months after surgery. In the control group, patients will be provided with grain powder for 2 months after surgery. The target for accrual is 168 patients. We divided in to three groups according to the type of surgery. DISCUSSION: The primary endpoint is to evaluate body cell mass index 2 months postoperatively. Secondary endpoints include other body composition changes as well as nutrition index and immune function change. We expect that ingestion of mealworms can effectively improve the nutritional status and enhance the immune function. Mealworm can be used effectively for nutritional management of patients after surgery.

trial registrationClinicaltrials.gov NCT03201926 Registered June 28, 2017, retrospectively registered.

Indexed as

Immune functionInvalid foodsMalnutritionNutritional balance

Identifiers

PMID32153957
PMCPMC7050863
OpenAlexW2989360441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.