Evidence map›Paper›PMID 32153944›Full record

ArticleBMC nutrition2019

Prevalence of vitamin D deficiency in pregnant women and their babies in Bhaktapur, Nepal.

Dhruba Shrestha, Saraswati Budhathoki, Sabi Pokhrel, Ashok Kumar Sah, Raj Kumar Shrestha, Ganendra Bhakta Raya, Reena Shrestha, Rasila Pasakhala, Christopher Smith, Bhim Gopal Dhoubhadel

Open access · goldAbstract read
In one paragraph

Article in BMC nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Dhruba ShresthaDepartment of Paediatrics, Siddhi Memorial Hospital, Bhaktapur, Nepal.ORCID 0000-0003-0218-5152
Saraswati BudhathokiDepartment of Paediatrics, Siddhi Memorial Hospital, Bhaktapur, Nepal.
Sabi PokhrelDepartment of Paediatrics, Siddhi Memorial Hospital, Bhaktapur, Nepal.
Ashok Kumar SahDepartment of Paediatrics, Siddhi Memorial Hospital, Bhaktapur, Nepal.
Raj Kumar ShresthaDepartment of Paediatrics, Siddhi Memorial Hospital, Bhaktapur, Nepal.
Ganendra Bhakta RayaDepartment of Paediatrics, Siddhi Memorial Hospital, Bhaktapur, Nepal.
Reena ShresthaDepartment of Paediatrics, Siddhi Memorial Hospital, Bhaktapur, Nepal.
Rasila PasakhalaDepartment of Paediatrics, Siddhi Memorial Hospital, Bhaktapur, Nepal.
Christopher Smith2School of Tropical Medicine and Global Health (TMGH), Nagasaki University, Nagasaki, Japan.
Bhim Gopal Dhoubhadel2School of Tropical Medicine and Global Health (TMGH), Nagasaki University, Nagasaki, Japan.
Bhaktapur Cancer Hospital · NPNagasaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D deficiency has been observed worldwide in pregnant women and their newborns. Maternal vitamin D deficiency can lead to deficiency in their newborn baby and has been linked with various complications during pregnancy and delivery. There is risk of premature delivery and it is associated with high neonatal mortality.

methodsSeventy-nine pregnant women who were admitted to the Siddhi Memorial Hospital for delivery and their newborn babies were enrolled in the study. Maternal blood samples were taken before delivery while umbilical cord blood samples of their babies were taken after delivery. Serum vitamin D level and calcium level were assessed by fluorescence immunoassay using Ichromax vitamin D kit and endpoint method, respectively in the Siddhi Memorial Hospital laboratory.

resultsMean +/- SD serum vitamin D and calcium levels in pregnant mother before delivery were 14.6 +/- 8.5 ng/ml and 8.0 +/- 0.5 mg/dl, respectively, and in the cord blood were 25.7 +/- 11.2 ng/ml and 8.6 +/- 0.9 mg/dl, respectively. Eighty-one percent of the mothers and 35.8% of their babies were found to have vitamin D deficiency. Although 97.5% of the pregnant women were taking calcium supplementation, serum calcium was found lower than the normal reference value in 67% of the pregnant women and 64.2% of their babies. There were a linear relationship between the maternal and baby's serum vitamin D (

conclusionThere is high prevalence of vitamin D and calcium deficiency in pregnant mothers and newborn babies in Bhaktapur, Nepal. Pregnant women need to be supplemented with adequate amounts of these nutrients.

Indexed as

AsiaCalciumDeficiencyNepalNewbornNutritionPregnancySupplementationVitamin D

Identifiers

PMID32153944
PMCPMC7050914
OpenAlexW2946837311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.