Evidence map›Paper›PMID 32153817›Full record

ArticleBMC nutrition2017

Supplementation of docosahexaenoic acid (DHA), vitamin D

Solvejg L Hansen, Anina Ritterband-Rosenbaum, Camilla B Voigt, Lars I Hellgren, Ann-Dorit M Sørensen, Charlotte Jacobsen, Line Z Greve, Katrine D Jørgensen, Peder E Bilde, Bente Kiens and 1 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02426554 (Dietary Supplementation of of DHA, Vitamin D3 and Uridine in Children), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02426554 nacompletednot on this map

Dietary Supplementation of of DHA, Vitamin D3 and Uridine in Children

TypeinterventionalSponsorUniversity of CopenhagenRan2011 to 2011Enrolled16ConditionsChildrenArmsDDU-supplement, Placebo supplement
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Solvejg L Hansen *1Department of Nutrition, Exercise and Sports, Section of Molecular Physiology, August Krogh Building University of Copenhagen, Universitetsparken 13, 2100 Copenhagen Ø, Denmark.
Anina Ritterband-Rosenbaum *2Center for Neuroscience, Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark.ORCID 0000-0002-3154-2537
Camilla B Voigt2Center for Neuroscience, Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark.
Lars I Hellgren3Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Søltofts Plads, 2800 Kgs. Lyngby, Denmark.
Ann-Dorit M Sørensen4National Food Institute, Division of Industrial Food Research, Technical University of Denmark, Søltofts Plads, 2800 Kgs. Lyngby, Denmark.
Charlotte Jacobsen4National Food Institute, Division of Industrial Food Research, Technical University of Denmark, Søltofts Plads, 2800 Kgs. Lyngby, Denmark.
Line Z GreveThe Elsass Institute, Holmegårdsvej 28, 2920 Charlottelund, Denmark.
Katrine D JørgensenThe Elsass Institute, Holmegårdsvej 28, 2920 Charlottelund, Denmark.
Peder E BildeThe Elsass Institute, Holmegårdsvej 28, 2920 Charlottelund, Denmark.
Bente Kiens1Department of Nutrition, Exercise and Sports, Section of Molecular Physiology, August Krogh Building University of Copenhagen, Universitetsparken 13, 2100 Copenhagen Ø, Denmark.
Jens B Nielsen2Center for Neuroscience, Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark.
University of Copenhagen · DKElsass Foundation · DKTechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLearning and memory have been shown to be influenced by combination of dietary supplements and exercise in animal models, but there is little available evidence from human subjects. The aim of this pilot study was to investigate the effect of combining a motor- and cognitive exercise program with dietary supplementation consisting of 500 mg docosahexaenoic acid (DHA), 10 μg vitamin D

methodsWe designed a randomized, placebo-controlled, double-blinded study lasting 6 weeks in which DDU-supplement or placebo was ingested daily. During the intervention period, all children trained approximately 30 min 3 days/week using an internet-based cognitive and motor training program (Mitii). Prior to and post the intervention period dietary record, blood sampling, physical exercise tests and motor and cognitive tests were performed.

resultsFourteen of the 16 children completed the intervention and ingested the supplement as required. 6 weeks DDU-supplementation resulted in a significant increase in the blood concentration of vitamin D

conclusionAll children showed improved performance in the trained motor- and cognitive tasks, but it was not possible to demonstrate any significant effects on the cognitive tests from the dietary supplementation. However, DDU-supplementation did result in increased blood concentration of DHA and vitamin D

trial registrationClinical registration ID: NCT02426554 (clinical Trial.gov). January 2015 retrospectively registered.

Indexed as

Blood samplesChildrenDHANutritional supplementPilot studyTrainingUridineVitamin D

Identifiers

PMID32153817
PMCPMC7050862
OpenAlexW2605787489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.