Evidence map›Paper›PMID 32153749›Full record

ArticleChemical science2019

A lipidomic workflow capable of resolving

Xue Zhao, Wenpeng Zhang, Donghui Zhang, Xinwei Liu, Wenbo Cao, Qinhua Chen, Zheng Ouyang, Yu Xia

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 76 citations in OpenAlex.

  1. Aziridination-Enabled Structural and Quantitative Lipidomics.Journal of the American Society for Mass Spectrometry · 2026
    Review
  2. Article
  3. Article
  4. Analytical applications of gas-phase ion chemistry enabled by mass spectrometry.Analytical methods : advancing methods and applications · 2026
    Review
  5. Article
  6. Article
  7. Structural Elucidation of Phosphatidylcholines via Radical-Directed Dissociation of [M + CuJournal of the American Society for Mass Spectrometry · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Dual Metal Electrolysis in Theta Capillary for Lipid Analysis.International journal of mass spectrometry · 2023
    Article
  15. Review
  16. Article
  17. RDD-HCD Provides Variable Fragmentation Routes Dictated by Radical Stability.Journal of the American Society for Mass Spectrometry · 2023
    Article
  18. Materials today. Bio · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Xue ZhaoMOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biological , Department of Chemistry , Tsinghua University , Beijing 100084 , China . Email: xiayu@mail.tsinghua.edu.cn.
Wenpeng ZhangDepartment of Chemistry , Purdue University , West Lafayette , IN 47907 , USA.ORCID 0000-0002-7018-930X
Donghui ZhangState Key Laboratory of Precision Measurement Technology and Instruments , Department of Precision Instrument , Tsinghua University , Beijing , 100084 , China.
Xinwei LiuState Key Laboratory of Precision Measurement Technology and Instruments , Department of Precision Instrument , Tsinghua University , Beijing , 100084 , China.
Wenbo CaoState Key Laboratory of Precision Measurement Technology and Instruments , Department of Precision Instrument , Tsinghua University , Beijing , 100084 , China.
Qinhua ChenAffiliated Dongfeng Hospital , Hubei University of Medicine , Shiyan , Hubei Province 442000 , China.ORCID 0000-0002-9108-1314
Zheng OuyangState Key Laboratory of Precision Measurement Technology and Instruments , Department of Precision Instrument , Tsinghua University , Beijing , 100084 , China.ORCID 0000-0002-7932-0933
Yu XiaMOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biological , Department of Chemistry , Tsinghua University , Beijing 100084 , China . Email: xiayu@mail.tsinghua.edu.cn.ORCID 0000-0001-8694-9900
Tsinghua University · CNInstitute of Bioorganic Chemistry · BYHubei University of Medicine · CNPurdue University West Lafayette · US

Funding

Mass spectrometry method with C=C location specificity for qualitative and quantitative lipid analysisR01GM118484 · NIGMS · PURDUE UNIVERSITY · PI MCLUCKEY, SCOTT A · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM118484
6 · The paper itself

Abstract

As a major class of mammalian lipids, phosphatidylcholines (PCs) often contain mixtures of structural isomers, resulting from different lipogenesis pathways. Profiling PCs at the isomer level, however, remains challenging in lipidomic settings, especially for characterizing the positions of fatty acyls on the glycerol backbone (

Identifiers

PMID32153749
PMCPMC7020929
OpenAlexW2978688426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.