Evidence map›Paper›PMID 32153520›Full record

ArticleFrontiers in microbiology2020

Phosphoprotein Gene of Wild-Type Rabies Virus Plays a Role in Limiting Viral Pathogenicity and Lowering the Enhancement of BBB Permeability.

Teng Long, Boyue Zhang, Ruqi Fan, Yuting Wu, Meijun Mo, Jun Luo, Yiran Chang, Qin Tian, Mingzhu Mei, He Jiang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Effective Use of Student-Created Case Studies as Assessment in an Undergraduate Neuroscience Course.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Teng LongCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Boyue ZhangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Ruqi FanCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Yuting WuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Meijun MoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Jun LuoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Yiran ChangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Qin TianCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Mingzhu MeiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
He JiangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Yongwen LuoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Xiaofeng GuoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
South China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhancement of blood-brain barrier (BBB) permeability is necessary for clearing virus in the central nervous system (CNS). It has been reported that only laboratory-attenuated rabies virus (RABV) induces inflammatory response to lead BBB transient breakdown rather than wild-type (wt) strains. As a component of ribonucleoprotein (RNP), phosphoprotein (P) of RABV plays a key role in viral replication and pathogenicity. To our knowledge, the function of RABV P gene during RABV invasion was unclear so far. In order to determine the role of RABV P gene during RABV infection, we evaluated the BBB permeability

Indexed as

blood–brain barrierGD-SH-01HEP-Fluryphosphoproteinviral replication

Identifiers

PMID32153520
PMCPMC7045047
OpenAlexW3007218228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.