Evidence map›Paper›PMID 32153512›Full record

ArticleFrontiers in endocrinology2020

Rare Variants in Genes Linked to Appetite Control and Hypothalamic Development in Early-Onset Severe Obesity.

Petra Loid, Taina Mustila, Riikka E Mäkitie, Heli Viljakainen, Anders Kämpe, Päivi Tossavainen, Marita Lipsanen-Nyman, Minna Pekkinen, Outi Mäkitie

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
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  5. AnResearch square · 2026
    Article
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  8. Article
  9. Review
  10. A Rare Case of Monogenic Obesity Due to a Novel Variant in theJournal of clinical research in pediatric endocrinology · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Treatment of Hypothalamic Obesity With GLP-1 Analogs.Journal of the Endocrine Society · 2024
    Review
  16. Protein-coding mutation inbioRxiv : the preprint server for biology · 2024
    Article
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Petra LoidChildren's Hospital, Helsinki University Hospital, Helsinki, Finland.
Taina MustilaDepartment of Pediatrics, Seinäjoki Central Hospital, Seinäjoki, Finland.
Riikka E MäkitieFolkhälsan Research Center, Genetics Research Program, Helsinki, Finland.
Heli ViljakainenFolkhälsan Research Center, Genetics Research Program, Helsinki, Finland.
Anders KämpeDepartment of Molecular Medicine and Surgery, Karolinska Institutet, and Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.
Päivi TossavainenDepartment of Children and Adolescents, PEDEGO Research Unit, University of Oulu, Oulu, Finland.
Marita Lipsanen-NymanChildren's Hospital, Helsinki University Hospital, Helsinki, Finland.
Minna PekkinenChildren's Hospital, Helsinki University Hospital, Helsinki, Finland.
Outi MäkitieChildren's Hospital, Helsinki University Hospital, Helsinki, Finland.
Karolinska University Hospital · SEUniversity of Helsinki · FIFolkhälsans Forskningscentrum · FIHammersmith Hospital · GBHelsinki Children's Hospital · FISeinäjoki University of Applied Sciences · FIUniversity of Oulu · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Polymorphism, Single NucleotideAdolescentAge of OnsetAppetite RegulationBiomarkersChildFemaleFinlandFollow-Up StudiesHumansHypothalamusMaleObesity, MorbidPediatric ObesityPedigreePhenotypeBiomarkersappetite regulationchildhood obesityhyperphagiahypothalamusMC4R

Identifiers

PMID32153512
PMCPMC7047210
OpenAlexW3006945365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.