Evidence map›Paper›PMID 32153425›Full record

ArticleFrontiers in physiology2020

Defining the Progression of Diabetic Cardiomyopathy in a Mouse Model of Type 1 Diabetes.

Miles J De Blasio, Nguyen Huynh, Minh Deo, Leslie E Dubrana, Jesse Walsh, Andrew Willis, Darnel Prakoso, Helen Kiriazis, Daniel G Donner, John C Chatham and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Guidelines for diet-induced models of cardiometabolic syndrome.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Lipoxin ACardiovascular diabetology · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Miles J De BlasioHeart Failure Pharmacology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Nguyen HuynhHeart Failure Pharmacology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Minh DeoHeart Failure Pharmacology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Leslie E DubranaHeart Failure Pharmacology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Jesse WalshHeart Failure Pharmacology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Andrew WillisHeart Failure Pharmacology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Darnel PrakosoHeart Failure Pharmacology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Helen KiriazisExperimental Cardiology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Daniel G DonnerExperimental Cardiology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
John C ChathamDepartment of Pathology, The University of Alabama at Birmingham, Birmingham, AL, United States.
Rebecca H RitchieHeart Failure Pharmacology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Baker Heart and Diabetes Institute · AUUniversity of Melbourne · AUMonash University · AUUniversity of Alabama at Birmingham · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

The incidence of diabetes and its association with increased cardiovascular disease risk represents a major health issue worldwide. Diabetes-induced hyperglycemia is implicated as a central driver of responses in the diabetic heart such as cardiomyocyte hypertrophy, fibrosis, and oxidative stress, termed diabetic cardiomyopathy. The onset of these responses in the setting of diabetes has not been studied to date. This study aimed to determine the time course of development of diabetic cardiomyopathy in a model of type 1 diabetes (T1D)

Indexed as

cardiac fibrosiscardiomyocyte hypertrophydiabetic cardiomyopathydiastolic dysfunctiontype 1 diabetes

Identifiers

PMID32153425
PMCPMC7045054
OpenAlexW3007339495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.