Evidence map›Paper›PMID 32153348›Full record

ArticleFrontiers in neuroscience2020

Structural and Functional Alterations in the Contralesional Medial Temporal Lobe in Glioma Patients.

Taoyang Yuan, Zhentao Zuo, Jianyou Ying, Lu Jin, Jie Kang, Songbai Gui, Rui Wang, Chuzhong Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Taoyang YuanBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Zhentao ZuoState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Jianyou YingBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Lu JinDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jie KangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Songbai GuiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Rui WangBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Chuzhong LiBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Capital Medical University · CNBeijing Tian Tan Hospital · CNBeijing Institute of Neurosurgery · CNChinese Academy of Sciences · CN

Funding

Effect of Prazosin on Alcohol Craving, Stress Dysregulation and Alcohol RelapseR01AA020504 · NIAAA · YALE UNIVERSITY · PI FOX, HELEN CECILIA, SINHA, RAJITA · 2012 to 2016
$2.7M
NIAAA NIH HHS R01 AA020504
6 · The paper itself

Abstract

backgroundThe human brain has an extraordinary ability to functionally change or reorganize its structure in response to disease. The aim of this study is to assess the structural and functional plasticity of contralesional medial temporal lobe (MTL) in patients with unilateral MTL glioma.

methodsSixty-eight patients with unilateral MTL glioma (left MTL glioma,

resultsCompared with healthy controls, both patient groups exhibited (1) a large cluster of voxels with gray matter (GM) volume decrease in the contralesional MTL using region of interest (ROI)-based VBM analysis (cluster level

conclusionUsing multi-modality brain imaging tools, we found structural and functional changes in the contralesional MTL in patients with unilateral MTL glioma. These findings suggest that the contralesional cortex may have decompensation of structure and function in patients with unilateral glioma, except for compensatory structural and functional adaptations. Our study provides additional insight into the neuroanatomical and functional network changes in the contralesional cortex in patients with glioma.

Indexed as

brain structure and functionfunctional connectivitygliomamedial temporal lobestructural magnetic resonance imaging analysis

Identifiers

PMID32153348
PMCPMC7044242
OpenAlexW3008391614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.