Evidence map›Paper›PMID 32153074›Full record

ArticleCell proliferation2020

Single cell imaging with near-field terahertz scanning microscopy.

Zaoxia Li, Shihan Yan, Ziyi Zang, Guoshuai Geng, Zhongbo Yang, Jiang Li, Lihua Wang, Chunyan Yao, Hong-Liang Cui, Chao Chang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cell proliferation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Review
  3. Quantitative imaging of individual bacterial cells:Journal of biomedical optics · 2025
    Article
  4. Article
  5. Article
  6. Biomedical application of terahertz imaging technology: a narrative review.Quantitative imaging in medicine and surgery · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Zaoxia LiCenter of Applied Physics & Chongqing Engineering Research Center of High-Resolution and Three-Dimensional Dynamic Imaging Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, China.ORCID https://orcid.org/0000-0003-2409-3590
Shihan YanCenter of Applied Physics & Chongqing Engineering Research Center of High-Resolution and Three-Dimensional Dynamic Imaging Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, China.ORCID https://orcid.org/0000-0001-9814-769X
Ziyi ZangCenter of Applied Physics & Chongqing Engineering Research Center of High-Resolution and Three-Dimensional Dynamic Imaging Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, China.
Guoshuai GengCenter of Applied Physics & Chongqing Engineering Research Center of High-Resolution and Three-Dimensional Dynamic Imaging Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, China.
Zhongbo YangCenter of Applied Physics & Chongqing Engineering Research Center of High-Resolution and Three-Dimensional Dynamic Imaging Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, China.
Jiang LiDivision of Physical Biology, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China.
Lihua WangDivision of Physical Biology, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China.
Chunyan YaoDepartment of Transfusion Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
Hong-Liang CuiCenter of Applied Physics & Chongqing Engineering Research Center of High-Resolution and Three-Dimensional Dynamic Imaging Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, China.
Chao ChangDepartment of Engineering Physics, Tsinghua University, Beijing, China.
Huabin WangCenter of Applied Physics & Chongqing Engineering Research Center of High-Resolution and Three-Dimensional Dynamic Imaging Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, China.ORCID https://orcid.org/0000-0001-5342-0672
Jilin University · CNChongqing Institute of Green and Intelligent Technology · CNChinese Academy of Sciences · CNArmy Medical University · CNNational University of Defense Technology · CN

Funding

Central Government Supported Key Instrument Program of China YXGYQ201700136Chongqing Collaborative Innovation Center for Brain ScienceNational Key Research and Development Program of China 2016YFC0101301National Key Research and Development Program of China 2016YFC0101302National Key Research and Development Program of China 2017YFF0106303National Natural Science Foundation of China (NSFC) 11604332National Natural Science Foundation of China (NSFC) 61875196National Natural Science Foundation of China (NSFC) U1932132Natural Science Foundation of Chongqing cstc2018jcyjAX0405Natural Science Foundation of Chongqing cstc2018jscx-msybX0084
6 · The paper itself

Abstract

objectivesTerahertz (THz)-based imaging techniques hold great potential for biological and biomedical applications, which nevertheless are hampered by the low spatial resolution of conventional THz imaging systems. In this work, we report a high-performance photoconductive antenna microprobe-based near-field THz time-domain spectroscopy scanning microscope. MATERIALS AND

methodsA single watermelon pulp cell was prepared on a clean quartz slide and covered by a thin polyethylene film. The high performance near-field THz microscope was developed based on a coherent THz time-domain spectroscopy system coupled with a photoconductive antenna microprobe. The sample was imaged in transmission mode.

resultsWe demonstrate the direct imaging of the morphology of single watermelon pulp cells in the natural dehydration process with our near-field THz microscope.

conclusionsGiven the label-free and non-destructive nature of THz detection techniques, our near-field microscopy-based single-cell imaging approach sheds new light on studying biological samples with THz.

Indexed as

CitrullusDesiccationEquipment DesignHumansMicroscopy, Scanning ProbeSingle-Cell AnalysisTerahertz Imagingdehydrationnear-field imagingphotoconductive antenna microprobescanning microscopesingle cellterahertz

Identifiers

PMID32153074
PMCPMC7162806
OpenAlexW3011359414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.