Evidence map›Paper›PMID 32152900›Full record

SynthesisJournal of robotic surgery2020

Port-site metastasis and atypical recurrences after robotic-assisted radical cystectomy (RARC): an updated comprehensive and systematic review of current evidences.

Guglielmo Mantica, Salvatore Smelzo, Francesca Ambrosini, Stefano Tappero, Stefano Parodi, Andrea Pacchetti, Davide De Marchi, Franco Gaboardi, Nazareno Suardi, Carlo Terrone

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of robotic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Images in urology - Metastatic urothelial carcinoma of the right vastus lateralis following robotic-assisted radical cystectomy.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Guglielmo ManticaDepartment of Urology, Policlinico San Martino Hospital, University of Genoa, Largo Rosanna Benzi 10, 16130, Genoa, Italy. guglielmo.mantica@gmail.com.ORCID http://orcid.org/0000-0003-4361-4523
Salvatore SmelzoDepartment of Urology, San Raffaele Turro Hospital, San Raffaele University, Milan, Italy.
Francesca AmbrosiniDepartment of Urology, Policlinico San Martino Hospital, University of Genoa, Largo Rosanna Benzi 10, 16130, Genoa, Italy.
Stefano TapperoDepartment of Urology, Policlinico San Martino Hospital, University of Genoa, Largo Rosanna Benzi 10, 16130, Genoa, Italy.
Stefano ParodiDepartment of Urology, Policlinico San Martino Hospital, University of Genoa, Largo Rosanna Benzi 10, 16130, Genoa, Italy.
Andrea PacchettiDepartment of Urology, Policlinico San Martino Hospital, University of Genoa, Largo Rosanna Benzi 10, 16130, Genoa, Italy.
Davide De MarchiDepartment of Urology, San Raffaele Turro Hospital, San Raffaele University, Milan, Italy.
Franco GaboardiDepartment of Urology, San Raffaele Turro Hospital, San Raffaele University, Milan, Italy.
Nazareno SuardiDepartment of Urology, Policlinico San Martino Hospital, University of Genoa, Largo Rosanna Benzi 10, 16130, Genoa, Italy.
Carlo TerroneDepartment of Urology, Policlinico San Martino Hospital, University of Genoa, Largo Rosanna Benzi 10, 16130, Genoa, Italy.
Ospedale Policlinico San Martino · ITSan Raffaele University of Rome · ITMartin University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this systematic review is to evaluate the current evidence regarding atypical metastases in patients undergoing robotic-assisted radical cystectomy (RARC). A review of the current literature was conducted through the Medline and NCBI PubMed, Cochrane Central Register of Controlled Trials (CENTRAL) and Google Scholar databases in October 2019. From the literature search using the cited keys and after a careful evaluation of the full texts, we included 31 articles in the study. Fourteen studies (45.2%) reported at least an atypical recurrence during the follow-up period with a rate between 4 and 40% of all the recurrences. Overall, 105 (1.63%) of the 6720 patients who have been evaluated in the included studies developed an atypical recurrence. Sixty-three (60%) of these atypical metastases were peritoneal carcinomatosis, 16 (15.2%) extrapelvic lymph nodes metastases, 11 (10.5%) port-site metastases, 10 (9.5%) retroperitoneal nodal metastases, while 5 (3.8%) patients developed more than one type of atypical recurrence. In literature, there is a low but not negligible incidence of atypical recurrences after RARC. However, publication bias and retrospective design of most studies could influence the evidences. Further prospective randomized studies are needed to clarify the real risk of patients undergoing RARC to develop atypical metastases.

Indexed as

Lymphatic MetastasisCarcinoma, Transitional CellCystectomyHumansNeoplasm Recurrence, LocalPeritoneal NeoplasmsRobotic Surgical ProceduresUrinary Bladder NeoplasmsAtypical recurrenceBladder cancerCystectomyPort-site metastasesRARC

Identifiers

PMID32152900
OpenAlexW3009741749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.