Evidence map›Paper›PMID 32152786›Full record

ReviewWorld journal of microbiology & biotechnology2020

Butanol production by Saccharomyces cerevisiae: perspectives, strategies and challenges.

Suéllen P H Azambuja, Rosana Goldbeck

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Overexpression of RuBisCO form I and II genes inApplied and environmental microbiology · 2024
    Article
  2. Article
  3. The potential of native and engineered Clostridia for biomass biorefining.Frontiers in bioengineering and biotechnology · 2024
    Review
  4. Evaluation of Cell Responses ofMicroorganisms · 2023
    Article
  5. Article
  6. Advances inJournal of fungi (Basel, Switzerland) · 2023
    Review
  7. Review
  8. Review
  9. Review
  10. Control ofMetabolites · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Suéllen P H AzambujaLaboratory of Bioprocesses and Metabolic Engineering, Department of Food Engineering, School of Food Engineering, University of Campinas, Rua Monteiro Lobato, 80, Campinas, SP, 13083-862, Brazil.
Rosana GoldbeckLaboratory of Bioprocesses and Metabolic Engineering, Department of Food Engineering, School of Food Engineering, University of Campinas, Rua Monteiro Lobato, 80, Campinas, SP, 13083-862, Brazil. rosana.goldbeck@gmail.com.ORCID http://orcid.org/0000-0003-2953-8050
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/08542-3Fundação de Amparo à Pesquisa do Estado de São Paulo (BR) 2015/20630-4
6 · The paper itself

Abstract

The search for gasoline substitutes has grown in recent decades, leading to the increased production of ethanol as viable alternative. However, research in recent years has shown that butanol exhibits various advantages over ethanol as a biofuel. Furthermore, butanol can also be used as a chemical platform, serving as an intermediate product and as a solvent in industrial reactions. This alcohol is naturally produced by some Clostridium species; however, Clostridial fermentation processes still have inherent problems, which focuses the interest on Saccharomyces cerevisiae for butanol production, as an alternative organism for the production of this alcohol. S. cerevisiae exhibits great adaptability to industrial conditions and can be modified with a wide range of genetic tools. Although S. cerevisiae is known to naturally produce isobutanol, the n-butanol synthesis pathway has not been well established in wild S. cerevisiae strains. Two strategies are most commonly used for of S. cerevisiae butanol production: the heterologous expression of the Clostridium pathway or the amino acid uptake pathways. However, butanol yields produced from S. cerevisiae are lower than ethanol yield. Thus, there are still many challenges needed to be overcome, which can be minimized through genetic and evolutive engineering, for butanol production by yeast to become a reality.

Indexed as

Biofuels1-ButanolBiosynthetic PathwaysButanolsClostridiumDrug ToleranceEthanolFermentationFungal ProteinsGene Expression Regulation, FungalIndustrial MicrobiologyMetabolic EngineeringSaccharomyces cerevisiaeSolvents1-ButanolBiofuelsButanolsEthanolFungal Proteinsisobutyl alcoholSolventsABE fermentationAmino acid pathwayButanol productionButanol toleranceSaccharomyces cerevisiae

Identifiers

PMID32152786
OpenAlexW3010207115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.