ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
A comparison between flow-regulated and adjustable valves used in hydrocephalus during infancy.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Management of ventriculomegaly in pediatric patients with syndromic craniosynostosis: a single center experience.Acta neurochirurgica · 2021Pooled it
- Incidence and management of overdrainage in pediatric hydrocephalus patients exclusively treated with modern gravitational VP shunt valves.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- The Evolution of Ventriculoperitoneal Shunt Valves and Why They Fail.World neurosurgery · 2025Review
- Article
- Revision rates of flow- versus pressure-regulated ventricular shunt valves for the treatment of hydrocephalus in neonates following germinal matrix haemorrhage-a retrospective review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Infant hydrocephalus: what valve first?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- Shunt technology for infants and a lifetime.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
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7 authors at 1 institution in 1 country.
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Abstract
introductionVentriculoperitoneal shunt insertion during the neonatal period and early infancy is associated with a high rate of shunt failure when compared to the adult population. Furthermore, the function of flow-regulated valves and differential pressure valves may be different in neonatal hydrocephalus.
methodsA retrospective case series of all primary shunt procedures carried out during or immediately following the neonatal period, from August 2011 to February 2018 at Sheffield Children's Hospital. The total sample size was 55. This included 34 patients with adjustable valves (Miethke ProGav) and 21 with flow-regulated valves (Orbis-Sigma); however, only 53 had adequate follow-up.
resultsThe overall 1 year shunt survival was 34% (18/53), and there was no significant difference depending on which shunt valve was implanted. The primary shunt infection rate was 11% (6/53) with S. aureus being the most common causative organism. During the first year of life, clinical signs of shunt overdrainage were seen more frequently in patients with adjustable valves than in those with flow-regulated valves (59% [19/32] versus 24% [5/21], p = 0.02). Furthermore, 2 patients in the adjustable valve group developed sagittal craniosynostosis secondary to shunt overdrainage.
conclusionShunt failure is high when inserted during or immediately following the neonatal period. Overdrainage may be less common in patients with flow-regulated valves. However, if overdrainage is observed, adjusting the setting of a differential pressure valve can effectively treat the overdrainage without the need for invasive shunt revision surgery.
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