Evidence map›Paper›PMID 32152653›Full record

ArticleIntensive care medicine2020

Unexpected cardiac arrests occurring inside the ICU: outcomes of a French prospective multicenter study.

Maxime Leloup, Isabelle Briatte, Alice Langlois, Alain Cariou, Olivier Lesieur, ACIR study group

2 registry-linked trialsAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03021564 completednot on this map

Prospective Multi-centre Observational Study on the Epidemiology, Risk Factors and Consequences of Unexpected Cardiac Arrest in Intensive Care Units.

TypeobservationalSponsorGroupe Hospitalier de la Rochelle Ré AunisRan2017 to 2018Enrolled677ConditionsHeart ArrestArmscardiopulmonary resuscitation
NCT04373759 completednot on this map

Cardiac Arrest Incidence and Outcome Among Patient With COVID-19 Pneumonia in French ICUs

Typeobservational_patient_registrySponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur MerRan2020 to 2020Enrolled186ConditionsSars-CoV2, Covid-19ArmsCardiopulmonary resuscitation, Modified Rankin score
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  17. Effects of COVID-19 on in-hospital cardiac arrest: incidence, causes, and outcome - a retrospective cohort study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Maxime LeloupIntensive Care Unit, Groupement Hospitalier La Rochelle Ré Aunis, 17000, La Rochelle, France.
Isabelle BriatteIntensive Care Unit, Groupement Hospitalier La Rochelle Ré Aunis, 17000, La Rochelle, France.
Alice LangloisIntensive Care Unit, Groupement Hospitalier La Rochelle Ré Aunis, 17000, La Rochelle, France.
Alain CariouMedical Intensive Care Unit, Cochin University Hospital, Paris, France.
Olivier LesieurIntensive Care Unit, Groupement Hospitalier La Rochelle Ré Aunis, 17000, La Rochelle, France. olivier.lesieur@gmail.com.
ACIR study group
Centre Hospitalier de La Rochelle · FRDélégation Paris 5 · FRHôpital Cochin · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCardiac arrest may occur unexpectedly in intensive care units (ICU). We hypothesize that certain patient characteristics and treatments are associated with survival and long-term functional outcome following in-ICU cardiac arrest.

methodsOver a 12-month period, cardiac arrests with resuscitation attempts were prospectively investigated in 45 French ICUs. Survivors were followed for 6 months.

resultsIn total, 677 (2.16%) of 31,399 admitted patients had at least one in-ICU cardiac arrest with resuscitation attempt, 42% of which occurred on the day of admission. In 79% cases, one or more condition(s) likely to promote the occurrence of cardiac arrest was/were identified, including hypoxia (179 patients), metabolic disorders (122), hypovolemia (94), and adverse events linked to the life-sustaining devices in place (98). Return of spontaneous circulation was achieved in 478 patients, of whom 163 were discharged alive from ICU and 146 from hospital. Six-month survival with no or moderate functional sequel (118 of 125 patients alive) correlated with a number of organ failures ≤ 2 when cardiac arrest occurred (OR 4.17 [1.92-9.09]), resuscitation time ≤ 5 min (3.32 [2.01-5.47]), shockable rhythm cardiac arrests (2.13 [1.26-3.45]) or related to the life-sustaining devices in place (2.11 [1.22-3.65]), absence of preexisting disability (1.98 [1.09-3.60]) or disease deemed fatal within 5 years (1.70 [1.05-2.77]), and sedation (1.71 [1.06-2.75]).

conclusionOnly one in six patients with in-ICU cardiac arrest and resuscitation attempt was alive at 6 months with good functional status. Certain characteristics specific to cardiac arrests, resuscitation maneuvers, and the pathological context in which they happen may help clarify prognosis and inform relatives.

Indexed as

Cardiopulmonary ResuscitationHeart ArrestHospitalizationHumansIntensive Care UnitsProspective StudiesCardiac arrestCardiopulmonary resuscitationIntensive care unitsPrognosis

Identifiers

PMID32152653
OpenAlexW3009942982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.